node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT10 | KRT14 | ENSP00000269576 | ENSP00000167586 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | 0.907 |
KRT10 | KRT16 | ENSP00000269576 | ENSP00000301653 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach- required for some inflammatory checkpoint for the skin barrier maintenance | 0.988 |
KRT10 | KRT18 | ENSP00000269576 | ENSP00000373487 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cytoskeletal 18; Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection; Keratins, type I | 0.912 |
KRT10 | KRT24 | ENSP00000269576 | ENSP00000264651 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cytoskeletal 24; Keratins, type I | 0.907 |
KRT10 | KRT25 | ENSP00000269576 | ENSP00000310573 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization | 0.901 |
KRT10 | KRT27 | ENSP00000269576 | ENSP00000301656 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) | 0.901 |
KRT10 | KRT32 | ENSP00000269576 | ENSP00000225899 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cuticular Ha2; Keratins, type I; Belongs to the intermediate filament family | 0.900 |
KRT10 | KRT37 | ENSP00000269576 | ENSP00000225550 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cuticular Ha7; Keratins, type I; Belongs to the intermediate filament family | 0.901 |
KRT10 | KRT38 | ENSP00000269576 | ENSP00000246646 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type I cuticular Ha8; Keratins, type I; Belongs to the intermediate filament family | 0.902 |
KRT10 | KRT76 | ENSP00000269576 | ENSP00000330101 | Keratin, type I cytoskeletal 10; Keratins, type I | Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification; Keratins, type II | 0.924 |
KRT14 | KRT10 | ENSP00000167586 | ENSP00000269576 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 10; Keratins, type I | 0.907 |
KRT14 | KRT16 | ENSP00000167586 | ENSP00000301653 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 16; Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach- required for some inflammatory checkpoint for the skin barrier maintenance | 0.967 |
KRT14 | KRT18 | ENSP00000167586 | ENSP00000373487 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 18; Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection; Keratins, type I | 0.906 |
KRT14 | KRT24 | ENSP00000167586 | ENSP00000264651 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 24; Keratins, type I | 0.907 |
KRT14 | KRT25 | ENSP00000167586 | ENSP00000310573 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization | 0.901 |
KRT14 | KRT27 | ENSP00000167586 | ENSP00000301656 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) | 0.903 |
KRT14 | KRT32 | ENSP00000167586 | ENSP00000225899 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cuticular Ha2; Keratins, type I; Belongs to the intermediate filament family | 0.904 |
KRT14 | KRT37 | ENSP00000167586 | ENSP00000225550 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cuticular Ha7; Keratins, type I; Belongs to the intermediate filament family | 0.901 |
KRT14 | KRT38 | ENSP00000167586 | ENSP00000246646 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type I cuticular Ha8; Keratins, type I; Belongs to the intermediate filament family | 0.901 |
KRT14 | KRT76 | ENSP00000167586 | ENSP00000330101 | Keratin, type I cytoskeletal 14; The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro | Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification; Keratins, type II | 0.932 |