• Version:
  • 11.0 [archived version]
STRINGSTRING
B3GNTL1 B3GNTL1 OXLD1 OXLD1 WDR45B WDR45B OGFOD2 OGFOD2 BAD BAD OGFOD3 OGFOD3 FCRL3 FCRL3 EFCAB1 EFCAB1 SERPINA6 SERPINA6 PGBD2 PGBD2
"OGFOD3" - 2-oxoglutarate and iron dependent oxygenase domain containing 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGFOD32-oxoglutarate and iron dependent oxygenase domain containing 3; Belongs to the OGFOD3 family (331 aa)    
Predicted Functional Partners:
OXLD1
Oxidoreductase-like domain-containing protein 1; Oxidoreductase like domain containing 1 (147 aa)
     
   
  0.794
WDR45B
WD repeat domain containing (344 aa)
           
  0.530
SERPINA6
Corticosteroid-binding globulin; Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species; Serpin peptidase inhibitors (405 aa)
           
  0.508
FCRL3
Fc receptor-like protein 3; Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells. Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly through association with SH2 domain-containing phosphatases. Inhibits cell tyrosine phosphorylation, calcium mobilization and activation-induced cell death induced through BCR signaling. Regulatory T-cells expressing FCRL3 exhibit a memory phenotyp [...] (734 aa)
           
  0.501
PGBD2
piggyBac transposable element derived 2; DNA transposon derived genes (592 aa)
           
  0.473
B3GNTL1
UDP-GlcNAc-betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Putative glycosyltransferase; Glycosyltransferase family 2 (361 aa)
     
   
  0.451
EFCAB1
EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1 (211 aa)
           
  0.440
OGFOD2
2-oxoglutarate and iron dependent oxygenase domain containing 2 (290 aa)
           
  0.439
BAD
Bcl2-associated agonist of cell death; Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways (168 aa)
           
  0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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