• Version:
  • 11.0 [archived version]
STRINGSTRING
BPIFA1 BPIFA1 TMEM125 TMEM125 ZDHHC15 ZDHHC15 LRRC23 LRRC23 C5orf34 C5orf34 LRRC36 LRRC36 CFAP45 CFAP45 ZNF391 ZNF391 TMEM178A TMEM178A C9orf131 C9orf131 CCDC13 CCDC13
"LRRC36" - Leucine-rich repeat-containing protein 36 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC36Leucine-rich repeat-containing protein 36; Leucine rich repeat containing 36 (754 aa)    
Predicted Functional Partners:
C9orf131
Uncharacterized protein C9orf131; Chromosome 9 open reading frame 131 (1079 aa)
           
  0.669
LRRC23
Leucine-rich repeat-containing protein 23; Leucine rich repeat containing 23 (343 aa)
     
   
  0.656
CFAP45
Cilia and flagella associated protein 45; Belongs to the CFAP45 family (551 aa)
           
  0.642
ZNF391
Zinc finger protein 391; May be involved in transcriptional regulation; Zinc fingers C2H2-type (358 aa)
           
  0.559
TMEM125
Transmembrane protein 125 (219 aa)
           
  0.515
C5orf34
Uncharacterized protein C5orf34; Chromosome 5 open reading frame 34 (638 aa)
           
  0.511
TMEM178A
Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family (297 aa)
           
  0.486
CCDC13
Coiled-coil domain-containing protein 13; Required for primary cilia formation and promotes the localization of the ciliopathy protein BBS4 to both centriolar satellites and cilia (715 aa)
           
  0.473
BPIFA1
BPI fold-containing family A member 1; Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Binds bacterial lipopolysaccharide (LPS). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory [...] (256 aa)
           
  0.449
ZDHHC15
Palmitoyltransferase ZDHHC15; Palmitoyltransferase specific for GAP43 and DLG4/PSD95; Belongs to the DHHC palmitoyltransferase family (337 aa)
           
  0.448
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]