• Version:
  • 11.0 [archived version]
STRINGSTRING
EFCAB14 EFCAB14 TRIM28 TRIM28 SLC35F3 SLC35F3 KIAA1324L KIAA1324L C14orf79 C14orf79 CDAN1 CDAN1 ZNF804B ZNF804B COL28A1 COL28A1 RALY RALY AKAP6 AKAP6 CSRNP3 CSRNP3
"ZNF804B" - Zinc finger protein 804B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF804BZinc finger protein 804B (1349 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
         
    0.900
RALY
RNA-binding protein Raly; RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (By similarity). May be a heterogeneous nuclear ribonucleoprotein (hnRNP); Belongs to the RRM HNRPC family. RALY subfamily (306 aa)
           
  0.659
C14orf79
Uncharacterized protein CLBA1; Chromosome 14 open reading frame 79 (325 aa)
           
  0.656
EFCAB14
EF-hand calcium-binding domain-containing protein 14; EF-hand calcium binding domain 14 (495 aa)
           
  0.532
KIAA1324L
UPF0577 protein KIAA1324-like; KIAA1324 like; Belongs to the UPF0577 family (1029 aa)
           
  0.522
AKAP6
A-kinase anchor protein 6; Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes; A-kinase anchoring proteins (2319 aa)
     
   
  0.520
COL28A1
Collagen alpha-1(XXVIII) chain; May act as a cell-binding protein; Belongs to the VWA-containing collagen family (1125 aa)
           
  0.519
SLC35F3
Putative thiamine transporter SLC35F3; May be a thiamine transporter; Belongs to the SLC35F solute transporter family (490 aa)
     
   
  0.493
CSRNP3
Cysteine/serine-rich nuclear protein 3; Binds to the consensus sequence 5’-AGAGTG-3’ and has transcriptional activator activity. Plays a role in apoptosis (By similarity); Protein phosphatase 1 regulatory subunits (585 aa)
     
   
  0.493
CDAN1
Codanin-1; May act as a negative regulator of ASF1 in chromatin assembly (1227 aa)
           
  0.493
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]