• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF200 ZNF200 SLC13A5 SLC13A5 ZNF337 ZNF337 SLC38A4 SLC38A4 FAM208B FAM208B SFI1 SFI1 PQLC2 PQLC2 EXPH5 EXPH5 SPTBN5 SPTBN5 TMEM208 TMEM208 ARL9 ARL9
"FAM208B" - Protein FAM208B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM208BProtein FAM208B; Family with sequence similarity 208 member B; Belongs to the FAM208 family (2430 aa)    
Predicted Functional Partners:
SFI1
Protein SFI1 homolog; Plays a role in the dynamic structure of centrosome- associated contractile fibers via its interaction with CETN2; Belongs to the SFI1 family (1242 aa)
           
  0.730
TMEM208
Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy (173 aa)
           
  0.709
SPTBN5
Spectrin beta, non-erythrocytic 5; Spectrins (3674 aa)
           
  0.695
EXPH5
Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking (1989 aa)
           
  0.695
PQLC2
Lysosomal amino acid transporter 1 homolog; Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes (291 aa)
           
  0.651
ZNF337
Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (751 aa)
           
  0.549
SLC38A4
Sodium-coupled neutral amino acid transporter 4; Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by His, Cys, Asn, Ser, Gly, Val, Thr, Gln and Met. May mediate sodium- independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with low transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5; Solute carriers (547 aa)
           
  0.539
SLC13A5
Solute carrier family 13 member 5; High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily (568 aa)
           
  0.536
ZNF200
Zinc finger protein 200; Could have a role in spermatogenesis; Zinc fingers C2H2-type (395 aa)
       
      0.536
ARL9
ADP-ribosylation factor-like protein 9; ADP ribosylation factor like GTPase 9; ARF GTPase family (123 aa)
           
  0.511
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]