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  • 11.0 [archived version]
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CCDC71L CCDC71L BCHE BCHE C11orf49 C11orf49 GCSAML GCSAML CLVS1 CLVS1 TRIM28 TRIM28 ZNF71 ZNF71 HDHD1 HDHD1 CENPI CENPI ZNF69 ZNF69 NMT2 NMT2
"ZNF71" - Endothelial zinc finger protein induced by tumor necrosis factor alpha in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ZNF71Endothelial zinc finger protein induced by tumor necrosis factor alpha; May be involved in transcriptional regulation; Zinc fingers C2H2-type (489 aa)    
Predicted Functional Partners:
ZNF69
Zinc finger protein 69; Zinc fingers C2H2-type (149 aa)
           
  0.906
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.903
CENPI
Centromere protein I; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the response of gonadal tissues to follicle-stimulating hormone; Constitutive centromere associated network (756 aa)
       
      0.544
HDHD1
Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family (251 aa)
 
       
  0.498
GCSAML
Germinal center associated signaling and motility like (135 aa)
           
  0.476
BCHE
Cholinesterase; Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters; Belongs to the type-B carboxylesterase/lipase family (602 aa)
           
  0.473
NMT2
Glycylpeptide N-tetradecanoyltransferase 2; Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins (498 aa)
           
  0.452
CCDC71L
Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like (235 aa)
           
  0.450
C11orf49
UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family (337 aa)
           
  0.448
CLVS1
Clavesin-1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (354 aa)
     
 
  0.447
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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