| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALG12 | DIRC1 | ENSP00000333813 | ENSP00000307860 | Dol-P-Man-Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation; Belongs to the glycosyltransferase 22 family | Disrupted in renal carcinoma 1 | 0.400 |
| ALG12 | KRBA2 | ENSP00000333813 | ENSP00000328017 | Dol-P-Man-Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation; Belongs to the glycosyltransferase 22 family | KRAB-A domain containing 2 | 0.450 |
| DIRC1 | ALG12 | ENSP00000307860 | ENSP00000333813 | Disrupted in renal carcinoma 1 | Dol-P-Man-Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation; Belongs to the glycosyltransferase 22 family | 0.400 |
| DIRC1 | KRBA2 | ENSP00000307860 | ENSP00000328017 | Disrupted in renal carcinoma 1 | KRAB-A domain containing 2 | 0.642 |
| GIN1 | KRBA2 | ENSP00000381970 | ENSP00000328017 | Gypsy retrotransposon integrase 1 | KRAB-A domain containing 2 | 0.587 |
| GPS2 | HDAC3 | ENSP00000370104 | ENSP00000302967 | G protein pathway suppressor 2; Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. May act as a regulator of adipogenisis (By similarity) | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 ’Lys- 27’ (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activ [...] | 0.969 |
| GPS2 | KRBA2 | ENSP00000370104 | ENSP00000328017 | G protein pathway suppressor 2; Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. May act as a regulator of adipogenisis (By similarity) | KRAB-A domain containing 2 | 0.542 |
| GPS2 | NCOR2 | ENSP00000370104 | ENSP00000384018 | G protein pathway suppressor 2; Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. May act as a regulator of adipogenisis (By similarity) | Nuclear receptor corepressor 2; Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival; Myb/SANT domain containing | 0.986 |
| GPS2 | TBL1XR1 | ENSP00000370104 | ENSP00000405574 | G protein pathway suppressor 2; Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. May act as a regulator of adipogenisis (By similarity) | F-box-like/WD repeat-containing protein TBL1XR1; F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation; Belongs to the WD repeat EBI family | 0.981 |
| HDAC3 | GPS2 | ENSP00000302967 | ENSP00000370104 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 ’Lys- 27’ (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activ [...] | G protein pathway suppressor 2; Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. May act as a regulator of adipogenisis (By similarity) | 0.969 |
| HDAC3 | KRBA2 | ENSP00000302967 | ENSP00000328017 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 ’Lys- 27’ (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activ [...] | KRAB-A domain containing 2 | 0.546 |
| HDAC3 | NCOR2 | ENSP00000302967 | ENSP00000384018 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 ’Lys- 27’ (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activ [...] | Nuclear receptor corepressor 2; Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival; Myb/SANT domain containing | 0.999 |
| HDAC3 | TBL1XR1 | ENSP00000302967 | ENSP00000405574 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 ’Lys- 27’ (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activ [...] | F-box-like/WD repeat-containing protein TBL1XR1; F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation; Belongs to the WD repeat EBI family | 0.990 |
| KRBA2 | ALG12 | ENSP00000328017 | ENSP00000333813 | KRAB-A domain containing 2 | Dol-P-Man-Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation; Belongs to the glycosyltransferase 22 family | 0.450 |
| KRBA2 | DIRC1 | ENSP00000328017 | ENSP00000307860 | KRAB-A domain containing 2 | Disrupted in renal carcinoma 1 | 0.642 |
| KRBA2 | GIN1 | ENSP00000328017 | ENSP00000381970 | KRAB-A domain containing 2 | Gypsy retrotransposon integrase 1 | 0.587 |
| KRBA2 | GPS2 | ENSP00000328017 | ENSP00000370104 | KRAB-A domain containing 2 | G protein pathway suppressor 2; Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction. May act as a regulator of adipogenisis (By similarity) | 0.542 |
| KRBA2 | HDAC3 | ENSP00000328017 | ENSP00000302967 | KRAB-A domain containing 2 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 ’Lys- 27’ (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activ [...] | 0.546 |
| KRBA2 | NCOR2 | ENSP00000328017 | ENSP00000384018 | KRAB-A domain containing 2 | Nuclear receptor corepressor 2; Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival; Myb/SANT domain containing | 0.542 |
| KRBA2 | NYNRIN | ENSP00000328017 | ENSP00000371994 | KRAB-A domain containing 2 | Protein NYNRIN; NYN domain and retroviral integrase containing | 0.670 |
