| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASPHD1 | C16orf53 | ENSP00000311447 | ENSP00000476774 | Aspartate beta-hydroxylase domain containing 1 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | 0.744 |
| ASPHD1 | C16orf54 | ENSP00000311447 | ENSP00000327506 | Aspartate beta-hydroxylase domain containing 1 | Transmembrane protein C16orf54; Chromosome 16 open reading frame 54 | 0.644 |
| ASPHD1 | C16orf92 | ENSP00000311447 | ENSP00000300575 | Aspartate beta-hydroxylase domain containing 1 | Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92 | 0.710 |
| ASPHD1 | FAM57B | ENSP00000311447 | ENSP00000369863 | Aspartate beta-hydroxylase domain containing 1 | Protein FAM57B; Involved in ceramide synthesis; TLC domain containing | 0.817 |
| ASPHD1 | GDPD3 | ENSP00000311447 | ENSP00000384363 | Aspartate beta-hydroxylase domain containing 1 | Lysophospholipase D GDPD3; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine | 0.763 |
| ASPHD1 | HIRIP3 | ENSP00000311447 | ENSP00000279392 | Aspartate beta-hydroxylase domain containing 1 | HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones | 0.688 |
| ASPHD1 | INO80E | ENSP00000311447 | ENSP00000457016 | Aspartate beta-hydroxylase domain containing 1 | INO80 complex subunit E; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair | 0.747 |
| ASPHD1 | PA1 | ENSP00000311447 | ENSP00000326519 | Aspartate beta-hydroxylase domain containing 1 | PAXIP1 associated glutamate rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | 0.744 |
| ASPHD1 | QPRT | ENSP00000311447 | ENSP00000378782 | Aspartate beta-hydroxylase domain containing 1 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA); Belongs to the NadC/ModD family | 0.543 |
| ASPHD1 | TMEM219 | ENSP00000311447 | ENSP00000457492 | Aspartate beta-hydroxylase domain containing 1 | Insulin-like growth factor-binding protein 3 receptor; Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding | 0.651 |
| C16orf53 | ASPHD1 | ENSP00000476774 | ENSP00000311447 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Aspartate beta-hydroxylase domain containing 1 | 0.744 |
| C16orf53 | C16orf54 | ENSP00000476774 | ENSP00000327506 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Transmembrane protein C16orf54; Chromosome 16 open reading frame 54 | 0.559 |
| C16orf53 | C16orf92 | ENSP00000476774 | ENSP00000300575 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Uncharacterized protein C16orf92; Chromosome 16 open reading frame 92 | 0.474 |
| C16orf53 | FAM57B | ENSP00000476774 | ENSP00000369863 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Protein FAM57B; Involved in ceramide synthesis; TLC domain containing | 0.641 |
| C16orf53 | GDPD3 | ENSP00000476774 | ENSP00000384363 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Lysophospholipase D GDPD3; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) and lysophosphatidylcholine (lyso-PC), and to a lesser extent for lysophosphatidylethanolamine (lyso-PE). Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine | 0.612 |
| C16orf53 | HIRIP3 | ENSP00000476774 | ENSP00000279392 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | HIRA-interacting protein 3; May play a role in chromatin function and histone metabolism via its interaction with HIRA and histones | 0.680 |
| C16orf53 | INO80E | ENSP00000476774 | ENSP00000457016 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | INO80 complex subunit E; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair | 0.596 |
| C16orf53 | PA1 | ENSP00000476774 | ENSP00000326519 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | PAXIP1 associated glutamate rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | 0.900 |
| C16orf53 | QPRT | ENSP00000476774 | ENSP00000378782 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA); Belongs to the NadC/ModD family | 0.447 |
| C16orf53 | TMEM219 | ENSP00000476774 | ENSP00000457492 | PAXIP1-associated glutamate-rich protein 1; Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1-PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned (By similarity). During immunoglobulin class switchin [...] | Insulin-like growth factor-binding protein 3 receptor; Cell death receptor specific for IGFBP3, may mediate caspase-8-dependent apoptosis upon ligand binding | 0.501 |
