node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1GALT1C1 | IGIP | ENSP00000304364 | ENSP00000327344 | C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | 0.439 |
C1GALT1C1 | MUC7 | ENSP00000304364 | ENSP00000407422 | C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili; Mucins | 0.921 |
CYSTM1 | IGIP | ENSP00000261811 | ENSP00000327344 | Cysteine-rich and transmembrane domain-containing protein 1; Cysteine rich transmembrane module containing 1 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | 0.491 |
IGIP | C1GALT1C1 | ENSP00000327344 | ENSP00000304364 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) | 0.439 |
IGIP | CYSTM1 | ENSP00000327344 | ENSP00000261811 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | Cysteine-rich and transmembrane domain-containing protein 1; Cysteine rich transmembrane module containing 1 | 0.491 |
IGIP | MUC7 | ENSP00000327344 | ENSP00000407422 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili; Mucins | 0.642 |
IGIP | PRM3 | ENSP00000327344 | ENSP00000325638 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | Protamine-3; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity) | 0.451 |
IGIP | RWDD4 | ENSP00000327344 | ENSP00000388920 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | RWD domain containing 4 | 0.473 |
IGIP | SLC32A1 | ENSP00000327344 | ENSP00000217420 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers | 0.400 |
IGIP | VIP | ENSP00000327344 | ENSP00000356213 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | VIP peptides; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder; Endogenous ligands | 0.594 |
MUC7 | C1GALT1C1 | ENSP00000407422 | ENSP00000304364 | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili; Mucins | C1GALT1-specific chaperone 1; Probable chaperone required for the generation of 1 O- glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Probably acts as a specific molecular chaperone assisting the folding/stability of core 1 beta-3-galactosyltransferase (C1GALT1) | 0.921 |
MUC7 | IGIP | ENSP00000407422 | ENSP00000327344 | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili; Mucins | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | 0.642 |
PRM3 | IGIP | ENSP00000325638 | ENSP00000327344 | Protamine-3; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity) | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | 0.451 |
RWDD4 | IGIP | ENSP00000388920 | ENSP00000327344 | RWD domain containing 4 | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | 0.473 |
SLC32A1 | IGIP | ENSP00000217420 | ENSP00000327344 | Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles; Solute carriers | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | 0.400 |
VIP | IGIP | ENSP00000356213 | ENSP00000327344 | VIP peptides; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder; Endogenous ligands | IgA-inducing protein homolog; Enhances IgA secretion from B-cells stimulated via CD40 | 0.594 |