• Version:
  • 11.0 [archived version]
STRINGSTRING
CASKIN2 CASKIN2 SLC35E1 SLC35E1 TMEM161A TMEM161A KIAA0195 KIAA0195 CHERP CHERP NR2C2AP NR2C2AP SLC25A42 SLC25A42 CIB3 CIB3 LRRC25 LRRC25 PGPEP1 PGPEP1 MEDAG MEDAG
"SLC25A42" - Mitochondrial coenzyme A transporter SLC25A42 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC25A42Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate; Solute carriers (318 aa)    
Predicted Functional Partners:
TMEM161A
Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis; Belongs to the TMEM161 family (479 aa)
     
   
  0.794
KIAA0195
Transmembrane protein 94; KIAA0195 (1356 aa)
     
   
  0.776
CASKIN2
Caskin-2; Sterile alpha motif domain containing (1202 aa)
           
  0.762
PGPEP1
Pyroglutamyl-peptidase 1; Removes 5-oxoproline from various penultimate amino acid residues except L-proline (209 aa)
           
  0.725
SLC35E1
Solute carrier family 35 member E1; Putative transporter; Solute carriers (410 aa)
     
   
  0.715
MEDAG
Mesenteric estrogen-dependent adipogenesis protein; Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes (303 aa)
           
  0.689
CHERP
Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation; G-patch domain containing (916 aa)
           
  0.685
CIB3
Calcium and integrin binding family member 3; EF-hand domain containing (187 aa)
     
   
  0.677
NR2C2AP
Nuclear receptor 2C2-associated protein; May act as a repressor of NR2C2-mediated transactivation by suppressing the binding between NR2C2/TR4 and the TR4-response element in target genes; Belongs to the NR2C2AP family (167 aa)
           
  0.670
LRRC25
Leucine-rich repeat-containing protein 25; May be involved in the activation of cells of innate and acquired immunity (305 aa)
           
  0.659
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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