LMBR1 protein (human) - STRING database

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LMBR1

Limb region 1 protein homolog; Putative membrane receptor (490 aa)

Predicted Functional Partners:

RNF32

0.877

SHH

0.831

ZP2

0.806

NOM1

0.744

PITX1

0.670

WNT8B

0.649

RBM33

0.596

MNX1

0.572

PMCH

0.570

EOGT

0.568

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EOGT	LMBR1	ENSP00000373206	ENSP00000326604	EGF domain-specific O-linked N-acetylglucosamine transferase; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains; O-linked N-acetylglucosaminyltransferases	Limb region 1 protein homolog; Putative membrane receptor	0.568
LMBR1	EOGT	ENSP00000326604	ENSP00000373206	Limb region 1 protein homolog; Putative membrane receptor	EGF domain-specific O-linked N-acetylglucosamine transferase; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N- acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains; O-linked N-acetylglucosaminyltransferases	0.568
LMBR1	MNX1	ENSP00000326604	ENSP00000252971	Limb region 1 protein homolog; Putative membrane receptor	Motor neuron and pancreas homeobox protein 1; Putative transcription factor involved in pancreas development and function; HOXL subclass homeoboxes	0.572
LMBR1	NOM1	ENSP00000326604	ENSP00000275820	Limb region 1 protein homolog; Putative membrane receptor	Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits	0.744
LMBR1	PITX1	ENSP00000326604	ENSP00000265340	Limb region 1 protein homolog; Putative membrane receptor	Pituitary homeobox 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb; Belongs to the paired homeobox family. Bicoid subfamily	0.670
LMBR1	PMCH	ENSP00000326604	ENSP00000332225	Limb region 1 protein homolog; Putative membrane receptor	Pro-MCH; MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal. May also have a role in spermatocyte differentiation; Belongs to the melanin-concentrating hormone family	0.570
LMBR1	RBM33	ENSP00000326604	ENSP00000384160	Limb region 1 protein homolog; Putative membrane receptor	RNA-binding protein 33; RNA binding motif containing	0.596
LMBR1	RNF32	ENSP00000326604	ENSP00000385285	Limb region 1 protein homolog; Putative membrane receptor	RING finger protein 32; May play a role in sperm formation; Ring finger proteins	0.877
LMBR1	SHH	ENSP00000326604	ENSP00000297261	Limb region 1 protein homolog; Putative membrane receptor	Sonic hedgehog protein; Sonic hedgehog protein- The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity); Hedgehog signaling molecule family	0.831
LMBR1	WNT8B	ENSP00000326604	ENSP00000340677	Limb region 1 protein homolog; Putative membrane receptor	Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus	0.649
LMBR1	ZP2	ENSP00000326604	ENSP00000460971	Limb region 1 protein homolog; Putative membrane receptor	Zona pellucida sperm-binding protein 2; The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor	0.806
MNX1	LMBR1	ENSP00000252971	ENSP00000326604	Motor neuron and pancreas homeobox protein 1; Putative transcription factor involved in pancreas development and function; HOXL subclass homeoboxes	Limb region 1 protein homolog; Putative membrane receptor	0.572
MNX1	NOM1	ENSP00000252971	ENSP00000275820	Motor neuron and pancreas homeobox protein 1; Putative transcription factor involved in pancreas development and function; HOXL subclass homeoboxes	Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits	0.613
MNX1	RNF32	ENSP00000252971	ENSP00000385285	Motor neuron and pancreas homeobox protein 1; Putative transcription factor involved in pancreas development and function; HOXL subclass homeoboxes	RING finger protein 32; May play a role in sperm formation; Ring finger proteins	0.654
MNX1	SHH	ENSP00000252971	ENSP00000297261	Motor neuron and pancreas homeobox protein 1; Putative transcription factor involved in pancreas development and function; HOXL subclass homeoboxes	Sonic hedgehog protein; Sonic hedgehog protein- The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity); Hedgehog signaling molecule family	0.586
NOM1	LMBR1	ENSP00000275820	ENSP00000326604	Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits	Limb region 1 protein homolog; Putative membrane receptor	0.744
NOM1	MNX1	ENSP00000275820	ENSP00000252971	Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits	Motor neuron and pancreas homeobox protein 1; Putative transcription factor involved in pancreas development and function; HOXL subclass homeoboxes	0.613
NOM1	RBM33	ENSP00000275820	ENSP00000384160	Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits	RNA-binding protein 33; RNA binding motif containing	0.717
NOM1	RNF32	ENSP00000275820	ENSP00000385285	Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus; Protein phosphatase 1 regulatory subunits	RING finger protein 32; May play a role in sperm formation; Ring finger proteins	0.893
PITX1	LMBR1	ENSP00000265340	ENSP00000326604	Pituitary homeobox 1; Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb; Belongs to the paired homeobox family. Bicoid subfamily	Limb region 1 protein homolog; Putative membrane receptor	0.670

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