node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASCC2 | CRNKL1 | ENSP00000380877 | ENSP00000366557 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | 0.719 |
ASCC2 | CWF19L1 | ENSP00000380877 | ENSP00000326411 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | CWF19-like protein 1; CWF19 like 1, cell cycle control | 0.753 |
ASCC2 | KANSL2 | ENSP00000380877 | ENSP00000415436 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | KAT8 regulatory NSL complex subunit 2; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription | 0.728 |
ASCC2 | PPIL3 | ENSP00000380877 | ENSP00000286175 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases | 0.589 |
ASCC2 | PPM1F | ENSP00000380877 | ENSP00000263212 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | Protein phosphatase 1F; Dephosphorylates and concomitantly deactivates CaM- kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis; Belongs to the PP2C family | 0.709 |
ASCC2 | PRPF19 | ENSP00000380877 | ENSP00000227524 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates ’Lys-63’-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Recruite [...] | 0.646 |
ASCC2 | ZNF830 | ENSP00000380877 | ENSP00000354518 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | Zinc finger protein 830; Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks for [...] | 0.619 |
CRNKL1 | ASCC2 | ENSP00000366557 | ENSP00000380877 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | 0.719 |
CRNKL1 | CWF19L1 | ENSP00000366557 | ENSP00000326411 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | CWF19-like protein 1; CWF19 like 1, cell cycle control | 0.773 |
CRNKL1 | KANSL2 | ENSP00000366557 | ENSP00000415436 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | KAT8 regulatory NSL complex subunit 2; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription | 0.729 |
CRNKL1 | PPIL3 | ENSP00000366557 | ENSP00000286175 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Cyclophilin peptidylprolyl isomerases | 0.969 |
CRNKL1 | PPM1F | ENSP00000366557 | ENSP00000263212 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | Protein phosphatase 1F; Dephosphorylates and concomitantly deactivates CaM- kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis; Belongs to the PP2C family | 0.691 |
CRNKL1 | PRPF19 | ENSP00000366557 | ENSP00000227524 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates ’Lys-63’-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Recruite [...] | 0.999 |
CRNKL1 | SLC2A13 | ENSP00000366557 | ENSP00000280871 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family | 0.752 |
CRNKL1 | SYF2 | ENSP00000366557 | ENSP00000236273 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | Pre-mRNA-splicing factor SYF2; May be involved in pre-mRNA splicing; Belongs to the SYF2 family | 0.999 |
CRNKL1 | ZNF830 | ENSP00000366557 | ENSP00000354518 | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | Zinc finger protein 830; Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks for [...] | 0.685 |
CWF19L1 | ASCC2 | ENSP00000326411 | ENSP00000380877 | CWF19-like protein 1; CWF19 like 1, cell cycle control | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | 0.753 |
CWF19L1 | CRNKL1 | ENSP00000326411 | ENSP00000366557 | CWF19-like protein 1; CWF19 like 1, cell cycle control | Crooked neck-like protein 1; Involved in pre-mRNA splicing process; Belongs to the crooked-neck family | 0.773 |
CWF19L1 | DBR1 | ENSP00000326411 | ENSP00000260803 | CWF19-like protein 1; CWF19 like 1, cell cycle control | Lariat debranching enzyme; Cleaves the 2’-5’ phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis; Belongs to the lariat debranching enzyme family | 0.769 |
CWF19L1 | KANSL2 | ENSP00000326411 | ENSP00000415436 | CWF19-like protein 1; CWF19 like 1, cell cycle control | KAT8 regulatory NSL complex subunit 2; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription | 0.773 |