| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CLVS2 | EFCAB11 | ENSP00000275162 | ENSP00000326267 | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.567 |
| EFCAB11 | CLVS2 | ENSP00000326267 | ENSP00000275162 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Clavesin-2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) | 0.567 |
| EFCAB11 | ENSG00000125954 | ENSP00000326267 | ENSP00000447121 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | cDNA FLJ59570, highly similar to Protein farnesyltransferase subunit beta (EC 2.5.1.58); CHURC1-FNTB readthrough | 0.654 |
| EFCAB11 | FNTB | ENSP00000326267 | ENSP00000246166 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C- terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X | 0.647 |
| EFCAB11 | GPR65 | ENSP00000326267 | ENSP00000267549 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Psychosine receptor; Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance. May have a role in activation-induced cell death or differentiation of T-cells (By similarity); G protein-coupled receptors, Class A orphans | 0.572 |
| EFCAB11 | LRRN3 | ENSP00000326267 | ENSP00000397312 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Leucine-rich repeat neuronal protein 3; Fibronectin type III domain containing | 0.566 |
| EFCAB11 | MYH10 | ENSP00000326267 | ENSP00000353590 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Myosin-10; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.634 |
| EFCAB11 | OBSCN | ENSP00000326267 | ENSP00000455507 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; Fibronectin type III domain containing | 0.601 |
| EFCAB11 | SPEG | ENSP00000326267 | ENSP00000311684 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Striated muscle preferentially expressed protein kinase; Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; I-set domain containing | 0.601 |
| EFCAB11 | STYXL1 | ENSP00000326267 | ENSP00000248600 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Serine/threonine/tyrosine-interacting-like protein 1; Probable pseudophosphatase. Contains a Ser residue instead of a conserved Cys residue in the dsPTPase catalytic loop which probably renders it catalytically inactive as a phosphatase. The binding pocket may be however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases; MAP kinase phosphatases | 0.546 |
| EFCAB11 | ZC3H14 | ENSP00000326267 | ENSP00000251038 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | Zinc finger CCCH domain-containing protein 14; Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides; Zinc fingers CCCH-type | 0.608 |
| ENSG00000125954 | EFCAB11 | ENSP00000447121 | ENSP00000326267 | cDNA FLJ59570, highly similar to Protein farnesyltransferase subunit beta (EC 2.5.1.58); CHURC1-FNTB readthrough | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.654 |
| FNTB | EFCAB11 | ENSP00000246166 | ENSP00000326267 | Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C- terminus of several proteins having the C-terminal sequence Cys- aliphatic-aliphatic-X | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.647 |
| GPR65 | EFCAB11 | ENSP00000267549 | ENSP00000326267 | Psychosine receptor; Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance. May have a role in activation-induced cell death or differentiation of T-cells (By similarity); G protein-coupled receptors, Class A orphans | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.572 |
| GPR65 | ZC3H14 | ENSP00000267549 | ENSP00000251038 | Psychosine receptor; Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance. May have a role in activation-induced cell death or differentiation of T-cells (By similarity); G protein-coupled receptors, Class A orphans | Zinc finger CCCH domain-containing protein 14; Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides; Zinc fingers CCCH-type | 0.494 |
| LRRN3 | EFCAB11 | ENSP00000397312 | ENSP00000326267 | Leucine-rich repeat neuronal protein 3; Fibronectin type III domain containing | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.566 |
| MYH10 | EFCAB11 | ENSP00000353590 | ENSP00000326267 | Myosin-10; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.634 |
| OBSCN | EFCAB11 | ENSP00000455507 | ENSP00000326267 | Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; Fibronectin type III domain containing | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.601 |
| SPEG | EFCAB11 | ENSP00000311684 | ENSP00000326267 | Striated muscle preferentially expressed protein kinase; Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells; I-set domain containing | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.601 |
| STYXL1 | EFCAB11 | ENSP00000248600 | ENSP00000326267 | Serine/threonine/tyrosine-interacting-like protein 1; Probable pseudophosphatase. Contains a Ser residue instead of a conserved Cys residue in the dsPTPase catalytic loop which probably renders it catalytically inactive as a phosphatase. The binding pocket may be however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases; MAP kinase phosphatases | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 | 0.546 |
