| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDHR3 | CDHR5 | ENSP00000325954 | ENSP00000351118 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Cadherin-related family member 5; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation; Cadherin related | 0.657 |
| CDHR3 | COG5 | ENSP00000325954 | ENSP00000297135 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | 0.520 |
| CDHR3 | EFCAB10 | ENSP00000325954 | ENSP00000418678 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10 | 0.471 |
| CDHR3 | GSDMB | ENSP00000325954 | ENSP00000415049 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Gasdermin-B; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable); Gasdermins | 0.575 |
| CDHR3 | NT5C1B | ENSP00000325954 | ENSP00000352904 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases | 0.489 |
| CDHR3 | ORMDL3 | ENSP00000325954 | ENSP00000377724 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | ORM1-like protein 3; Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling; Belongs to the ORM family | 0.557 |
| CDHR3 | POM121L1P | ENSP00000325954 | ENSP00000481613 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | annotation not available | 0.473 |
| CDHR3 | SH3YL1 | ENSP00000325954 | ENSP00000348471 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | SH3 domain-containing YSC84-like protein 1; SH3 and SYLF domain containing 1 | 0.546 |
| CDHR3 | SYPL1 | ENSP00000325954 | ENSP00000011473 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Synaptophysin-like protein 1; Synaptophysin like 1; Belongs to the synaptophysin/synaptobrevin family | 0.588 |
| CDHR3 | VANGL2 | ENSP00000325954 | ENSP00000357040 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | Vang-like protein 2; Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity) | 0.485 |
| CDHR5 | CDHR3 | ENSP00000351118 | ENSP00000325954 | Cadherin-related family member 5; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation; Cadherin related | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.657 |
| COG5 | CDHR3 | ENSP00000297135 | ENSP00000325954 | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.520 |
| EFCAB10 | CDHR3 | ENSP00000418678 | ENSP00000325954 | EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10 | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.471 |
| EFCAB10 | NT5C1B | ENSP00000418678 | ENSP00000352904 | EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10 | Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases | 0.550 |
| EFCAB10 | SH3YL1 | ENSP00000418678 | ENSP00000348471 | EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10 | SH3 domain-containing YSC84-like protein 1; SH3 and SYLF domain containing 1 | 0.594 |
| GSDMB | CDHR3 | ENSP00000415049 | ENSP00000325954 | Gasdermin-B; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable); Gasdermins | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.575 |
| GSDMB | ORMDL3 | ENSP00000415049 | ENSP00000377724 | Gasdermin-B; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable); Gasdermins | ORM1-like protein 3; Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling; Belongs to the ORM family | 0.916 |
| NT5C1B | CDHR3 | ENSP00000352904 | ENSP00000325954 | Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases | Cadherin-related family member 3; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types | 0.489 |
| NT5C1B | EFCAB10 | ENSP00000352904 | ENSP00000418678 | Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases | EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10 | 0.550 |
| NT5C1B | SH3YL1 | ENSP00000352904 | ENSP00000348471 | Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases | SH3 domain-containing YSC84-like protein 1; SH3 and SYLF domain containing 1 | 0.490 |
