STK25 protein (human) - STRING database

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STK25

Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration (426 aa)

Predicted Functional Partners:

PDCD10

0.999

STRN

0.961

STRIP1

0.949

MOB4

0.947

STRIP2

0.945

STRN4

0.930

SLMAP

0.913

STRN3

0.912

FGFR1OP2

0.908

CAB39

0.904

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAB39	STK25	ENSP00000258418	ENSP00000325748	Calcium-binding protein 39; Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1	Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration	0.904
FGFR1OP2	MOB4	ENSP00000229395	ENSP00000315702	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	0.939
FGFR1OP2	PDCD10	ENSP00000229395	ENSP00000376506	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity); Belongs to the PDCD10 family	0.926
FGFR1OP2	SLMAP	ENSP00000229395	ENSP00000295951	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; STRIPAK complex	0.883
FGFR1OP2	STK25	ENSP00000229395	ENSP00000325748	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration	0.908
FGFR1OP2	STRIP1	ENSP00000229395	ENSP00000358810	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; STRIPAK complex	0.963
FGFR1OP2	STRIP2	ENSP00000229395	ENSP00000249344	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin-interacting protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Belongs to the STRIP family	0.882
FGFR1OP2	STRN	ENSP00000229395	ENSP00000263918	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin; Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling; Belongs to the WD repeat striatin family	0.937
FGFR1OP2	STRN3	ENSP00000229395	ENSP00000350071	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Protein phosphatase 2 regulatory subunits	0.916
FGFR1OP2	STRN4	ENSP00000229395	ENSP00000375777	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family	0.791
MOB4	FGFR1OP2	ENSP00000315702	ENSP00000229395	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	0.939
MOB4	PDCD10	ENSP00000315702	ENSP00000376506	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity); Belongs to the PDCD10 family	0.967
MOB4	SLMAP	ENSP00000315702	ENSP00000295951	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; STRIPAK complex	0.953
MOB4	STK25	ENSP00000315702	ENSP00000325748	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration	0.947
MOB4	STRIP1	ENSP00000315702	ENSP00000358810	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape; STRIPAK complex	0.970
MOB4	STRIP2	ENSP00000315702	ENSP00000249344	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin-interacting protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape; Belongs to the STRIP family	0.962
MOB4	STRN	ENSP00000315702	ENSP00000263918	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin; Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling; Belongs to the WD repeat striatin family	0.995
MOB4	STRN3	ENSP00000315702	ENSP00000350071	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Protein phosphatase 2 regulatory subunits	0.960
MOB4	STRN4	ENSP00000315702	ENSP00000375777	MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family	Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family	0.972
PDCD10	FGFR1OP2	ENSP00000376506	ENSP00000229395	Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity); Belongs to the PDCD10 family	FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family	0.926

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