node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD19 | CD22 | ENSP00000437940 | ENSP00000085219 | B-lymphocyte antigen CD19; Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation; CD molecules | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act [...] | 0.960 |
CD19 | CD37 | ENSP00000437940 | ENSP00000325708 | B-lymphocyte antigen CD19; Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation; CD molecules | Leukocyte antigen CD37; CD37 molecule | 0.689 |
CD19 | CD52 | ENSP00000437940 | ENSP00000363330 | B-lymphocyte antigen CD19; Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation; CD molecules | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | 0.751 |
CD19 | ENSG00000250349 | ENSP00000437940 | ENSP00000417050 | B-lymphocyte antigen CD19; Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation; CD molecules | Tetraspanin; Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7 | 0.440 |
CD22 | CD19 | ENSP00000085219 | ENSP00000437940 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act [...] | B-lymphocyte antigen CD19; Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation; CD molecules | 0.960 |
CD22 | CD37 | ENSP00000085219 | ENSP00000325708 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act [...] | Leukocyte antigen CD37; CD37 molecule | 0.673 |
CD22 | CD52 | ENSP00000085219 | ENSP00000363330 | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act [...] | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | 0.688 |
CD37 | CD19 | ENSP00000325708 | ENSP00000437940 | Leukocyte antigen CD37; CD37 molecule | B-lymphocyte antigen CD19; Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation; CD molecules | 0.689 |
CD37 | CD22 | ENSP00000325708 | ENSP00000085219 | Leukocyte antigen CD37; CD37 molecule | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act [...] | 0.673 |
CD37 | CD52 | ENSP00000325708 | ENSP00000363330 | Leukocyte antigen CD37; CD37 molecule | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | 0.625 |
CD37 | CLEC7A | ENSP00000325708 | ENSP00000302569 | Leukocyte antigen CD37; CD37 molecule | C-type lectin domain family 7 member A; Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimula [...] | 0.646 |
CD37 | ENSG00000250349 | ENSP00000325708 | ENSP00000417050 | Leukocyte antigen CD37; CD37 molecule | Tetraspanin; Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7 | 0.673 |
CD37 | MYSM1 | ENSP00000325708 | ENSP00000418734 | Leukocyte antigen CD37; CD37 molecule | Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation; Myb/SANT domain containing | 0.635 |
CD37 | PBDC1 | ENSP00000325708 | ENSP00000362456 | Leukocyte antigen CD37; CD37 molecule | Protein PBDC1; Polysaccharide biosynthesis domain containing 1; Belongs to the PBDC1 family | 0.642 |
CD37 | TM4SF1 | ENSP00000325708 | ENSP00000304277 | Leukocyte antigen CD37; CD37 molecule | Transmembrane 4 L six family member 1 | 0.628 |
CD37 | TSPAN32 | ENSP00000325708 | ENSP00000182290 | Leukocyte antigen CD37; CD37 molecule | Tetraspanin-32; Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family | 0.634 |
CD37 | UPK1A | ENSP00000325708 | ENSP00000478942 | Leukocyte antigen CD37; CD37 molecule | Uroplakin-1a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity); Belongs to the tetraspanin (TM4SF) family | 0.622 |
CD52 | CD19 | ENSP00000363330 | ENSP00000437940 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | B-lymphocyte antigen CD19; Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation; CD molecules | 0.751 |
CD52 | CD22 | ENSP00000363330 | ENSP00000085219 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | B-cell receptor CD22; Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act [...] | 0.688 |
CD52 | CD37 | ENSP00000363330 | ENSP00000325708 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Leukocyte antigen CD37; CD37 molecule | 0.625 |