• Version:
  • 11.0 [archived version]
STRINGSTRING
GLB1 GLB1 KANK4 KANK4 TRAPPC2 TRAPPC2 TRAPPC1 TRAPPC1 STMN4 STMN4 TRAPPC5 TRAPPC5 C7orf43 C7orf43 AP1S1 AP1S1 CABS1 CABS1 BCL2L14 BCL2L14 NAT16 NAT16
"C7orf43" - Uncharacterized protein C7orf43 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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[Homology]
Score
C7orf43Uncharacterized protein C7orf43; Chromosome 7 open reading frame 43 (580 aa)    
Predicted Functional Partners:
NAT16
Probable N-acetyltransferase 16; Probable N-acetyltransferase. Shows only trace activity toward L-His and no N-acetyltransferase activity toward other amino acids. The physiological substrate of this enzyme is unknown; GCN5 related N-acetyltransferases (369 aa)
           
  0.856
TRAPPC1
Trafficking protein particle complex subunit 1; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET5 subfamily (145 aa)
       
      0.827
CABS1
Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1 (395 aa)
       
      0.823
KANK4
KN motif and ankyrin repeat domain-containing protein 4; May be involved in the control of cytoskeleton formation by regulating actin polymerization; Ankyrin repeat domain containing (995 aa)
       
      0.816
STMN4
Stathmin-4; Stathmin 4; Stathmins (216 aa)
       
      0.816
BCL2L14
Apoptosis facilitator Bcl-2-like protein 14; Plays a role in apoptosis; Belongs to the Bcl-2 family (327 aa)
       
      0.816
TRAPPC2
Trafficking protein particle complex subunit 2; Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. Sedlin subfamily (174 aa)
       
      0.812
TRAPPC5
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily (188 aa)
       
      0.811
GLB1
Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans; Belongs to the glycosyl hydrolase 35 family (677 aa)
       
      0.768
AP1S1
AP-1 complex subunit sigma-1A; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (158 aa)
           
  0.737
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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