node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAI1 | BAIAP2 | ENSP00000430945 | ENSP00000316338 | Adhesion G protein-coupled receptor B1; Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity. In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells. Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner. Inhibits MDM2-mediated ubiquitination and de [...] | Brain-specific angiogenesis inhibitor 1-associated protein 2; Adapter protein that links membrane-bound small G- proteins to cytoplasmic effector proteins. Necessary for CDC42- mediated reorganization of the actin cytoskeleton and for RAC1- mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling [...] | 0.685 |
BAI1 | BAIAP3 | ENSP00000430945 | ENSP00000324510 | Adhesion G protein-coupled receptor B1; Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity. In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells. Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner. Inhibits MDM2-mediated ubiquitination and de [...] | BAI1 associated protein 3; C2 domain containing | 0.767 |
BAIAP2 | BAI1 | ENSP00000316338 | ENSP00000430945 | Brain-specific angiogenesis inhibitor 1-associated protein 2; Adapter protein that links membrane-bound small G- proteins to cytoplasmic effector proteins. Necessary for CDC42- mediated reorganization of the actin cytoskeleton and for RAC1- mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling [...] | Adhesion G protein-coupled receptor B1; Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity. In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells. Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner. Inhibits MDM2-mediated ubiquitination and de [...] | 0.685 |
BAIAP2 | BAIAP3 | ENSP00000316338 | ENSP00000324510 | Brain-specific angiogenesis inhibitor 1-associated protein 2; Adapter protein that links membrane-bound small G- proteins to cytoplasmic effector proteins. Necessary for CDC42- mediated reorganization of the actin cytoskeleton and for RAC1- mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling [...] | BAI1 associated protein 3; C2 domain containing | 0.729 |
BAIAP3 | BAI1 | ENSP00000324510 | ENSP00000430945 | BAI1 associated protein 3; C2 domain containing | Adhesion G protein-coupled receptor B1; Phosphatidylserine receptor which enhances the engulfment of apoptotic cells. Also mediates the binding and engulfment of Gram-negative bacteria. Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity. In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells. Promotes myoblast fusion (By similarity). Activates the Rho pathway in a G-protein-dependent manner. Inhibits MDM2-mediated ubiquitination and de [...] | 0.767 |
BAIAP3 | BAIAP2 | ENSP00000324510 | ENSP00000316338 | BAI1 associated protein 3; C2 domain containing | Brain-specific angiogenesis inhibitor 1-associated protein 2; Adapter protein that links membrane-bound small G- proteins to cytoplasmic effector proteins. Necessary for CDC42- mediated reorganization of the actin cytoskeleton and for RAC1- mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling [...] | 0.729 |
BAIAP3 | CCDC169 | ENSP00000324510 | ENSP00000426174 | BAI1 associated protein 3; C2 domain containing | Coiled-coil domain containing 169 | 0.708 |
BAIAP3 | CLMP | ENSP00000324510 | ENSP00000405577 | BAI1 associated protein 3; C2 domain containing | CXADR-like membrane protein; May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development; I-set domain containing | 0.591 |
BAIAP3 | GABRQ | ENSP00000324510 | ENSP00000469332 | BAI1 associated protein 3; C2 domain containing | Gamma-aminobutyric acid receptor subunit theta; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits | 0.692 |
BAIAP3 | IPO13 | ENSP00000324510 | ENSP00000361418 | BAI1 associated protein 3; C2 domain containing | Importin-13; Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis r [...] | 0.800 |
BAIAP3 | KCNK12 | ENSP00000324510 | ENSP00000327611 | BAI1 associated protein 3; C2 domain containing | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity); Potassium two pore domain channel subfamily K | 0.696 |
BAIAP3 | SCTR | ENSP00000324510 | ENSP00000019103 | BAI1 associated protein 3; C2 domain containing | Secretin receptor; This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Glucagon receptor family | 0.675 |
BAIAP3 | SYTL4 | ENSP00000324510 | ENSP00000362080 | BAI1 associated protein 3; C2 domain containing | Synaptotagmin-like protein 4; Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner (By similarity); Synaptotagmin like tandem C2 proteins | 0.720 |
BAIAP3 | WBSCR17 | ENSP00000324510 | ENSP00000329654 | BAI1 associated protein 3; C2 domain containing | Polypeptide N-acetylgalactosaminyltransferase 17; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor | 0.702 |
CCDC169 | BAIAP3 | ENSP00000426174 | ENSP00000324510 | Coiled-coil domain containing 169 | BAI1 associated protein 3; C2 domain containing | 0.708 |
CCDC169 | CLMP | ENSP00000426174 | ENSP00000405577 | Coiled-coil domain containing 169 | CXADR-like membrane protein; May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development; I-set domain containing | 0.526 |
CCDC169 | GABRQ | ENSP00000426174 | ENSP00000469332 | Coiled-coil domain containing 169 | Gamma-aminobutyric acid receptor subunit theta; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Gamma-aminobutyric acid type A receptor subunits | 0.695 |
CCDC169 | KCNK12 | ENSP00000426174 | ENSP00000327611 | Coiled-coil domain containing 169 | Potassium channel subfamily K member 12; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel (By similarity); Potassium two pore domain channel subfamily K | 0.677 |
CCDC169 | WBSCR17 | ENSP00000426174 | ENSP00000329654 | Coiled-coil domain containing 169 | Polypeptide N-acetylgalactosaminyltransferase 17; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor | 0.685 |
CLMP | BAIAP3 | ENSP00000405577 | ENSP00000324510 | CXADR-like membrane protein; May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development; I-set domain containing | BAI1 associated protein 3; C2 domain containing | 0.591 |