MTURN protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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Predicted Interactions

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Score

MTURN

Maturin; May be involved in early neuronal development (131 aa)

Predicted Functional Partners:

PLEKHA8

0.780

RSPRY1

0.724

EFCAB1

0.723

METTL6

0.704

GPATCH3

0.700

EAF1

0.700

FAM192A

0.691

IMPAD1

0.667

ENTPD3

0.661

SNX20

0.654

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAF1	EFCAB1	ENSP00000380054	ENSP00000262103	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	0.789
EAF1	ENTPD3	ENSP00000380054	ENSP00000301825	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	Ectonucleoside triphosphate diphosphohydrolase 3; Has a threefold preference for the hydrolysis of ATP over ADP	0.743
EAF1	FAM192A	ENSP00000380054	ENSP00000335808	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	Protein FAM192A; Family with sequence similarity 192 member A	0.768
EAF1	GPATCH3	ENSP00000380054	ENSP00000354645	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6; G [...]	0.770
EAF1	METTL6	ENSP00000380054	ENSP00000407613	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	Methyltransferase-like protein 6; Probable methyltransferase	0.825
EAF1	MTURN	ENSP00000380054	ENSP00000324204	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	Maturin; May be involved in early neuronal development	0.700
EAF1	PLEKHA8	ENSP00000380054	ENSP00000397947	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by [...]	0.744
EAF1	RSPRY1	ENSP00000380054	ENSP00000443176	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	Ring finger and SPRY domain containing 1	0.790
EAF1	SNX20	ENSP00000380054	ENSP00000332062	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	Sorting nexin-20; May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion	0.748
EFCAB1	EAF1	ENSP00000262103	ENSP00000380054	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	0.789
EFCAB1	ENTPD3	ENSP00000262103	ENSP00000301825	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	Ectonucleoside triphosphate diphosphohydrolase 3; Has a threefold preference for the hydrolysis of ATP over ADP	0.763
EFCAB1	FAM192A	ENSP00000262103	ENSP00000335808	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	Protein FAM192A; Family with sequence similarity 192 member A	0.800
EFCAB1	GPATCH3	ENSP00000262103	ENSP00000354645	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6; G [...]	0.766
EFCAB1	METTL6	ENSP00000262103	ENSP00000407613	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	Methyltransferase-like protein 6; Probable methyltransferase	0.791
EFCAB1	MTURN	ENSP00000262103	ENSP00000324204	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	Maturin; May be involved in early neuronal development	0.723
EFCAB1	PLEKHA8	ENSP00000262103	ENSP00000397947	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by [...]	0.745
EFCAB1	RSPRY1	ENSP00000262103	ENSP00000443176	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	Ring finger and SPRY domain containing 1	0.824
EFCAB1	SNX20	ENSP00000262103	ENSP00000332062	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	Sorting nexin-20; May play a role in cellular vesicle trafficking. Has been proposed to function as a sorting protein that targets SELPLG into endosomes, but has no effect on SELPLG internalization from the cell surface, or on SELPLG-mediated cell-cell adhesion	0.790
ENTPD3	EAF1	ENSP00000301825	ENSP00000380054	Ectonucleoside triphosphate diphosphohydrolase 3; Has a threefold preference for the hydrolysis of ATP over ADP	ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities; Belongs to the EAF family	0.743
ENTPD3	EFCAB1	ENSP00000301825	ENSP00000262103	Ectonucleoside triphosphate diphosphohydrolase 3; Has a threefold preference for the hydrolysis of ATP over ADP	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1	0.763

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