ZNF771 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZNF771

Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type (317 aa)

Predicted Functional Partners:

TRIM28

0.921

RCOR3

0.662

ZNF512

0.517

BAZ2B

0.487

LIMD2

0.482

LBX1

0.455

TMEM177

0.426

TMEM101

0.406

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAZ2B	RCOR3	ENSP00000376534	ENSP00000413929	Bromodomain adjacent to zinc finger domain protein 2B; May play a role in transcriptional regulation interacting with ISWI; Belongs to the WAL family	REST corepressor 3; May act as a component of a corepressor complex that represses transcription; Belongs to the CoREST family	0.507
BAZ2B	ZNF771	ENSP00000376534	ENSP00000323945	Bromodomain adjacent to zinc finger domain protein 2B; May play a role in transcriptional regulation interacting with ISWI; Belongs to the WAL family	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.487
LBX1	ZNF771	ENSP00000359212	ENSP00000323945	Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord; NKL subclass homeoboxes and pseudogenes	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.455
LIMD2	ZNF771	ENSP00000259006	ENSP00000323945	LIM domain-containing protein 2; Acts as an activator of the protein-kinase ILK, thereby regulating cell motility; LIM domain containing	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.482
RCOR3	BAZ2B	ENSP00000413929	ENSP00000376534	REST corepressor 3; May act as a component of a corepressor complex that represses transcription; Belongs to the CoREST family	Bromodomain adjacent to zinc finger domain protein 2B; May play a role in transcriptional regulation interacting with ISWI; Belongs to the WAL family	0.507
RCOR3	ZNF771	ENSP00000413929	ENSP00000323945	REST corepressor 3; May act as a component of a corepressor complex that represses transcription; Belongs to the CoREST family	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.662
TMEM101	TMEM177	ENSP00000468025	ENSP00000402661	Transmembrane protein 101; May activate NF-kappa-B signaling pathways	Transmembrane protein 177	0.562
TMEM101	ZNF771	ENSP00000468025	ENSP00000323945	Transmembrane protein 101; May activate NF-kappa-B signaling pathways	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.406
TMEM177	TMEM101	ENSP00000402661	ENSP00000468025	Transmembrane protein 177	Transmembrane protein 101; May activate NF-kappa-B signaling pathways	0.562
TMEM177	ZNF771	ENSP00000402661	ENSP00000323945	Transmembrane protein 177	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.426
TRIM28	ZNF771	ENSP00000253024	ENSP00000323945	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.921
ZNF512	ZNF771	ENSP00000347648	ENSP00000323945	Zinc finger protein 512; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.517
ZNF771	BAZ2B	ENSP00000323945	ENSP00000376534	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Bromodomain adjacent to zinc finger domain protein 2B; May play a role in transcriptional regulation interacting with ISWI; Belongs to the WAL family	0.487
ZNF771	LBX1	ENSP00000323945	ENSP00000359212	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord; NKL subclass homeoboxes and pseudogenes	0.455
ZNF771	LIMD2	ENSP00000323945	ENSP00000259006	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	LIM domain-containing protein 2; Acts as an activator of the protein-kinase ILK, thereby regulating cell motility; LIM domain containing	0.482
ZNF771	RCOR3	ENSP00000323945	ENSP00000413929	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	REST corepressor 3; May act as a component of a corepressor complex that represses transcription; Belongs to the CoREST family	0.662
ZNF771	TMEM101	ENSP00000323945	ENSP00000468025	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Transmembrane protein 101; May activate NF-kappa-B signaling pathways	0.406
ZNF771	TMEM177	ENSP00000323945	ENSP00000402661	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Transmembrane protein 177	0.426
ZNF771	TRIM28	ENSP00000323945	ENSP00000253024	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	0.921
ZNF771	ZNF512	ENSP00000323945	ENSP00000347648	Zinc finger protein 771; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Zinc finger protein 512; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.517

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2020

Credits

Access

Info

About