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  • 11.0 [archived version]
STRINGSTRING
BLOC1S1 BLOC1S1 SPATA25 SPATA25 BLOC1S5 BLOC1S5 TEX37 TEX37 TEX35 TEX35 OOSP2 OOSP2 RGSL1 RGSL1 GRIP1 GRIP1 RALGPS2 RALGPS2 FAM160B1 FAM160B1 C1orf100 C1orf100
"TEX35" - Testis-expressed protein 35 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TEX35Testis-expressed protein 35; Testis expressed 35 (233 aa)    
Predicted Functional Partners:
RGSL1
Regulator of G protein signaling like 1 (1076 aa)
     
   
  0.910
RALGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing (583 aa)
           
  0.908
SPATA25
Spermatogenesis-associated protein 25; May play a role in spermatogenesis; Belongs to the SPATA25 family (227 aa)
           
  0.810
TEX37
Testis-expressed sequence 37 protein; Testis expressed 37 (180 aa)
     
   
  0.809
BLOC1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. As part of the BORC complex may play a role in lysosomes movemen [...] (153 aa)
       
      0.653
BLOC1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking; Belongs to th [...] (187 aa)
       
      0.653
GRIP1
Glutamate receptor-interacting protein 1; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity); PDZ domain containing (1076 aa)
           
  0.645
OOSP2
Oocyte secreted protein 2 (158 aa)
           
  0.640
C1orf100
Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100 (147 aa)
           
  0.571
FAM160B1
Protein FAM160B1; Family with sequence similarity 160 member B1; Armadillo-like helical domain containing (765 aa)
           
  0.560
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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