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  • 11.0 [archived version]
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WSCD1 WSCD1 LYSMD3 LYSMD3 C15orf26 C15orf26 MTHFSD MTHFSD TMEM82 TMEM82 MYCBPAP MYCBPAP RSAD1 RSAD1 DPY30 DPY30 AKAP1 AKAP1 ARL6 ARL6 MYCBP MYCBP
"MYCBPAP" - MYCBP-associated protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
MYCBPAPMYCBP-associated protein; May play a role in spermatogenesis. May be involved in synaptic processes (By similarity) (984 aa)    
Predicted Functional Partners:
MYCBP
c-Myc-binding protein; May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC (103 aa)
       
 
  0.939
ARL6
ADP-ribosylation factor-like protein 6; Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent [...] (186 aa)
           
  0.771
AKAP1
A-kinase anchor protein 1, mitochondrial; Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane; A-kinase anchoring proteins (903 aa)
     
   
  0.758
WSCD1
WSC domain containing 1 (575 aa)
           
  0.598
RSAD1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis; Belongs to the anaerobic coproporphyrinogen-III oxidase family (442 aa)
 
       
  0.587
MTHFSD
Methenyltetrahydrofolate synthase domain-containing protein; Methenyltetrahydrofolate synthetase domain containing; RNA binding motif containing (383 aa)
           
  0.577
LYSMD3
LysM and putative peptidoglycan-binding domain-containing protein 3; LysM domain containing 3 (306 aa)
           
  0.539
C15orf26
Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly (301 aa)
           
  0.530
TMEM82
Transmembrane protein 82 (343 aa)
           
  0.515
DPY30
Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at ’Lys-4’, particularly trimethylation. Histone H3 ’Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 ’Lys-4’ methylation at key developmental loci. May also play an indirect or direct role in endosomal transport; Belongs to the dpy-30 family (99 aa)
     
   
  0.504
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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