TMEM168 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMEM168

Transmembrane protein 168; Belongs to the TMEM168 family (697 aa)

Predicted Functional Partners:

FAM174A

0.804

OLFML1

0.775

CCDC70

0.647

C7orf60

0.623

ARHGAP20

0.587

ARMCX2

0.585

TMEM63B

0.576

IFI27L2

0.565

ADNP2

0.549

MRPL57

0.542

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADNP2	ARHGAP20	ENSP00000262198	ENSP00000260283	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	0.572
ADNP2	ARMCX2	ENSP00000262198	ENSP00000331662	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	0.576
ADNP2	CCDC70	ENSP00000262198	ENSP00000242819	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	Coiled-coil domain containing 70	0.574
ADNP2	MRPL57	ENSP00000262198	ENSP00000310726	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	Mitochondrial ribosomal protein L57; Belongs to the mitochondrion-specific ribosomal protein mL63 family	0.513
ADNP2	TMEM168	ENSP00000262198	ENSP00000323068	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	Transmembrane protein 168; Belongs to the TMEM168 family	0.549
ADNP2	TMEM63B	ENSP00000262198	ENSP00000259746	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	CSC1-like protein 2; Acts as an osmosensitive calcium-permeable cation channel	0.555
ARHGAP20	ADNP2	ENSP00000260283	ENSP00000262198	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	0.572
ARHGAP20	ARMCX2	ENSP00000260283	ENSP00000331662	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	0.666
ARHGAP20	CCDC70	ENSP00000260283	ENSP00000242819	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Coiled-coil domain containing 70	0.517
ARHGAP20	MRPL57	ENSP00000260283	ENSP00000310726	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Mitochondrial ribosomal protein L57; Belongs to the mitochondrion-specific ribosomal protein mL63 family	0.538
ARHGAP20	TMEM168	ENSP00000260283	ENSP00000323068	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	Transmembrane protein 168; Belongs to the TMEM168 family	0.587
ARHGAP20	TMEM63B	ENSP00000260283	ENSP00000259746	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	CSC1-like protein 2; Acts as an osmosensitive calcium-permeable cation channel	0.577
ARMCX2	ADNP2	ENSP00000331662	ENSP00000262198	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	0.576
ARMCX2	ARHGAP20	ENSP00000331662	ENSP00000260283	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state	0.666
ARMCX2	CCDC70	ENSP00000331662	ENSP00000242819	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	Coiled-coil domain containing 70	0.593
ARMCX2	MRPL57	ENSP00000331662	ENSP00000310726	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	Mitochondrial ribosomal protein L57; Belongs to the mitochondrion-specific ribosomal protein mL63 family	0.546
ARMCX2	TMEM168	ENSP00000331662	ENSP00000323068	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	Transmembrane protein 168; Belongs to the TMEM168 family	0.585
ARMCX2	TMEM63B	ENSP00000331662	ENSP00000259746	Armadillo repeat-containing X-linked protein 2; May regulate the dynamics and distribution of mitochondria in neural cells; Armadillo repeat containing	CSC1-like protein 2; Acts as an osmosensitive calcium-permeable cation channel	0.583
C7orf60	TMEM168	ENSP00000297145	ENSP00000323068	Probable methyltransferase BMT2 homolog; Probable S-adenosyl-L-methionine-dependent methyltransferase	Transmembrane protein 168; Belongs to the TMEM168 family	0.623
CCDC70	ADNP2	ENSP00000242819	ENSP00000262198	Coiled-coil domain containing 70	Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; ZF class homeoboxes and pseudogenes	0.574

page 1 of 3

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About