C4orf17 protein (human) - STRING database

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C4orf17

Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17 (359 aa)

Predicted Functional Partners:

ARRDC5

0.796

LKAAEAR1

0.793

NT5C1B

0.727

TDRD12

0.702

DNAJC17

0.510

FOXJ2

0.488

C10orf11

0.476

ZNF512

0.475

ZNF536

0.473

TREML4

0.473

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRDC5	C4orf17	ENSP00000371200	ENSP00000322582	Arrestin domain containing 5; Belongs to the arrestin family	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	0.796
ARRDC5	LKAAEAR1	ENSP00000371200	ENSP00000310801	Arrestin domain containing 5; Belongs to the arrestin family	Protein LKAAEAR1; LKAAEAR motif containing 1	0.703
ARRDC5	NT5C1B	ENSP00000371200	ENSP00000352904	Arrestin domain containing 5; Belongs to the arrestin family	Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases	0.650
ARRDC5	TDRD12	ENSP00000371200	ENSP00000390621	Arrestin domain containing 5; Belongs to the arrestin family	Putative ATP-dependent RNA helicase TDRD12; Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary [...]	0.549
C10orf11	C4orf17	ENSP00000361577	ENSP00000322582	Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	0.476
C4orf17	ARRDC5	ENSP00000322582	ENSP00000371200	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Arrestin domain containing 5; Belongs to the arrestin family	0.796
C4orf17	C10orf11	ENSP00000322582	ENSP00000361577	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Leucine-rich melanocyte differentiation-associated protein; Required for melanocyte differentiation	0.476
C4orf17	DNAJC17	ENSP00000322582	ENSP00000220496	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	0.510
C4orf17	FOXJ2	ENSP00000322582	ENSP00000162391	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Forkhead box protein J2; Transcriptional activator. Able to bind to two different type of DNA binding sites. Isoform FOXJ2.L behaves as a more potent transactivator than FOXJ2.S; Forkhead boxes	0.488
C4orf17	LKAAEAR1	ENSP00000322582	ENSP00000310801	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Protein LKAAEAR1; LKAAEAR motif containing 1	0.793
C4orf17	NT5C1B	ENSP00000322582	ENSP00000352904	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases	0.727
C4orf17	TDRD12	ENSP00000322582	ENSP00000390621	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Putative ATP-dependent RNA helicase TDRD12; Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary [...]	0.702
C4orf17	TREML4	ENSP00000322582	ENSP00000342570	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Trem-like transcript 4 protein; Positively regulates Toll-like receptor TLR7 signaling in macrophages; V-set domain containing	0.473
C4orf17	ZNF512	ENSP00000322582	ENSP00000347648	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Zinc finger protein 512; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.475
C4orf17	ZNF536	ENSP00000322582	ENSP00000347730	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	Zinc finger protein 536; May be involved in transcriptional regulation. Recognizes and binds 2 copies of the core DNA sequence 5’-CCCCCA- 3’; Zinc fingers C2H2-type	0.473
DNAJC17	C4orf17	ENSP00000220496	ENSP00000322582	DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription; DNAJ heat shock proteins	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	0.510
FOXJ2	C4orf17	ENSP00000162391	ENSP00000322582	Forkhead box protein J2; Transcriptional activator. Able to bind to two different type of DNA binding sites. Isoform FOXJ2.L behaves as a more potent transactivator than FOXJ2.S; Forkhead boxes	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	0.488
LKAAEAR1	ARRDC5	ENSP00000310801	ENSP00000371200	Protein LKAAEAR1; LKAAEAR motif containing 1	Arrestin domain containing 5; Belongs to the arrestin family	0.703
LKAAEAR1	C4orf17	ENSP00000310801	ENSP00000322582	Protein LKAAEAR1; LKAAEAR motif containing 1	Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17	0.793
LKAAEAR1	NT5C1B	ENSP00000310801	ENSP00000352904	Protein LKAAEAR1; LKAAEAR motif containing 1	Cytosolic 5’-nucleotidase 1B; Dephosphorylates the 5’ and 2’(3’)-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity); 5’-nucleotidases	0.671

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