TNNI3K protein (human) - STRING database

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TNNI3K

Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily (835 aa)

Predicted Functional Partners:

TNNI3

0.890

ENSG00000259030

0.806

LRRIQ3

0.775

FPGT

0.750

SEC16B

0.716

GNPDA2

0.685

FAIM2

0.676

TMEM18

0.670

QPCTL

0.670

POC5

0.669

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSG00000259030	LRRIQ3	ENSP00000450895	ENSP00000346414	FPGT-TNNI3K readthrough; Ankyrin repeat domain containing	Leucine rich repeats and IQ motif containing 3	0.819
ENSG00000259030	TNNI3K	ENSP00000450895	ENSP00000322251	FPGT-TNNI3K readthrough; Ankyrin repeat domain containing	Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily	0.806
FAIM2	GNPDA2	ENSP00000321951	ENSP00000295448	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	Glucosamine-6-phosphate deaminase 2	0.742
FAIM2	POC5	ENSP00000321951	ENSP00000410216	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family	0.559
FAIM2	QPCTL	ENSP00000321951	ENSP00000012049	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	Glutaminyl-peptide cyclotransferase-like protein; Responsible for the biosynthesis of pyroglutamyl peptides	0.568
FAIM2	SEC16B	ENSP00000321951	ENSP00000308339	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	Protein transport protein Sec16B; Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization; Belongs to the SEC16 family	0.741
FAIM2	TMEM18	ENSP00000321951	ENSP00000281017	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	Transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC); Belongs to the TMEM18 family	0.732
FAIM2	TNNI3K	ENSP00000321951	ENSP00000322251	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily	0.676
FPGT	LRRIQ3	ENSP00000359935	ENSP00000346414	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	Leucine rich repeats and IQ motif containing 3	0.752
FPGT	TNNI3K	ENSP00000359935	ENSP00000322251	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily	0.750
GNPDA2	FAIM2	ENSP00000295448	ENSP00000321951	Glucosamine-6-phosphate deaminase 2	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	0.742
GNPDA2	POC5	ENSP00000295448	ENSP00000410216	Glucosamine-6-phosphate deaminase 2	Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family	0.646
GNPDA2	QPCTL	ENSP00000295448	ENSP00000012049	Glucosamine-6-phosphate deaminase 2	Glutaminyl-peptide cyclotransferase-like protein; Responsible for the biosynthesis of pyroglutamyl peptides	0.681
GNPDA2	SEC16B	ENSP00000295448	ENSP00000308339	Glucosamine-6-phosphate deaminase 2	Protein transport protein Sec16B; Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization; Belongs to the SEC16 family	0.860
GNPDA2	TMEM18	ENSP00000295448	ENSP00000281017	Glucosamine-6-phosphate deaminase 2	Transmembrane protein 18; Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor cells (NPC); Belongs to the TMEM18 family	0.891
GNPDA2	TNNI3K	ENSP00000295448	ENSP00000322251	Glucosamine-6-phosphate deaminase 2	Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily	0.685
LRRIQ3	ENSG00000259030	ENSP00000346414	ENSP00000450895	Leucine rich repeats and IQ motif containing 3	FPGT-TNNI3K readthrough; Ankyrin repeat domain containing	0.819
LRRIQ3	FPGT	ENSP00000346414	ENSP00000359935	Leucine rich repeats and IQ motif containing 3	Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids	0.752
LRRIQ3	TNNI3K	ENSP00000346414	ENSP00000322251	Leucine rich repeats and IQ motif containing 3	Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily	0.775
POC5	FAIM2	ENSP00000410216	ENSP00000321951	Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family	Protein lifeguard 2; Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development; Belongs to the BI1 family. LFG subfamily	0.559

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