| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC8 | NKPD1 | ENSP00000303158 | ENSP00000321976 | Coiled-coil domain-containing protein 8; Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Required for localization of CUL7 to the centrosome; Protein phosphatase 1 regulatory subunits | NTPase KAP family P-loop domain containing 1 | 0.731 |
| CLASRP | CLPTM1 | ENSP00000221455 | ENSP00000336994 | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family | 0.693 |
| CLASRP | GEMIN7 | ENSP00000221455 | ENSP00000270257 | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | 0.534 |
| CLASRP | NKPD1 | ENSP00000221455 | ENSP00000321976 | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | NTPase KAP family P-loop domain containing 1 | 0.778 |
| CLASRP | TRAPPC6A | ENSP00000221455 | ENSP00000006275 | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | Trafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes; Trafficking protein particle complex | 0.661 |
| CLASRP | ZNF296 | ENSP00000221455 | ENSP00000302770 | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | Zinc finger protein 296; May be a transcriptional corepressor with KLF4; Zinc fingers C2H2-type | 0.605 |
| CLPTM1 | CLASRP | ENSP00000336994 | ENSP00000221455 | Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | 0.693 |
| CLPTM1 | GEMIN7 | ENSP00000336994 | ENSP00000270257 | Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family | Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | 0.503 |
| CLPTM1 | NKPD1 | ENSP00000336994 | ENSP00000321976 | Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family | NTPase KAP family P-loop domain containing 1 | 0.732 |
| CLPTM1 | TRAPPC6A | ENSP00000336994 | ENSP00000006275 | Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family | Trafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes; Trafficking protein particle complex | 0.547 |
| CLPTM1 | ZNF296 | ENSP00000336994 | ENSP00000302770 | Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family | Zinc finger protein 296; May be a transcriptional corepressor with KLF4; Zinc fingers C2H2-type | 0.563 |
| GEMIN7 | CLASRP | ENSP00000270257 | ENSP00000221455 | Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | 0.534 |
| GEMIN7 | CLPTM1 | ENSP00000270257 | ENSP00000336994 | Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family | 0.503 |
| GEMIN7 | NKPD1 | ENSP00000270257 | ENSP00000321976 | Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | NTPase KAP family P-loop domain containing 1 | 0.605 |
| GEMIN7 | TRAPPC6A | ENSP00000270257 | ENSP00000006275 | Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | Trafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes; Trafficking protein particle complex | 0.479 |
| GEMIN7 | ZNF296 | ENSP00000270257 | ENSP00000302770 | Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...] | Zinc finger protein 296; May be a transcriptional corepressor with KLF4; Zinc fingers C2H2-type | 0.457 |
| HORMAD2 | NKPD1 | ENSP00000336984 | ENSP00000321976 | HORMA domain-containing protein 2; Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint- required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal [...] | NTPase KAP family P-loop domain containing 1 | 0.508 |
| LRRC71 | NKPD1 | ENSP00000336661 | ENSP00000321976 | Leucine-rich repeat-containing protein 71; Leucine rich repeat containing 71 | NTPase KAP family P-loop domain containing 1 | 0.477 |
| NKPD1 | CCDC8 | ENSP00000321976 | ENSP00000303158 | NTPase KAP family P-loop domain containing 1 | Coiled-coil domain-containing protein 8; Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Required for localization of CUL7 to the centrosome; Protein phosphatase 1 regulatory subunits | 0.731 |
| NKPD1 | CLASRP | ENSP00000321976 | ENSP00000221455 | NTPase KAP family P-loop domain containing 1 | CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family | 0.778 |
