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  • 11.0 [archived version]
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FAM150A FAM150A PRAC1 PRAC1 SLC13A5 SLC13A5 ZSCAN18 ZSCAN18 RIMS4 RIMS4 FAM78A FAM78A PCDHAC1 PCDHAC1 ZNF671 ZNF671 TRIM28 TRIM28 KHDRBS2 KHDRBS2 RXFP3 RXFP3
"ZNF671" - Zinc finger protein 671 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF671Zinc finger protein 671; May be involved in transcriptional regulation; Zinc fingers C2H2-type (534 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.928
PCDHAC1
Protocadherin alpha-C1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (963 aa)
       
 
  0.671
FAM78A
Protein FAM78A; Family with sequence similarity 78 member A; Belongs to the FAM78 family (283 aa)
           
  0.648
RIMS4
Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis (270 aa)
     
   
  0.632
FAM150A
ALK and LTK ligand 1; Ligand for receptor tyrosine kinase LTK and perhaps receptor tyrosine kinase ALK; activation of ALK is reported conflictingly (129 aa)
           
  0.559
PRAC1
PRAC1 small nuclear protein (57 aa)
           
  0.540
KHDRBS2
KH domain-containing, RNA-binding, signal transduction-associated protein 2; RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin [...] (349 aa)
     
 
  0.534
ZSCAN18
Zinc finger and SCAN domain-containing protein 18; May be involved in transcriptional regulation; SCAN domain containing (566 aa)
     
   
  0.490
RXFP3
Relaxin-3 receptor 1; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation; Relaxin family peptide receptors (469 aa)
       
 
  0.479
SLC13A5
Solute carrier family 13 member 5; High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily (568 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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