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STRINGSTRING
RPL26L1 RPL26L1 ASB2 ASB2 KBTBD2 KBTBD2 MYADML2 MYADML2 PAQR7 PAQR7 PAQR4 PAQR4 STX1B STX1B PAQR6 PAQR6 PAQR9 PAQR9 FLYWCH1 FLYWCH1 KIAA1586 KIAA1586
"PAQR4" - Progestin and adipoQ receptor family member 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PAQR4Progestin and adipoQ receptor family member 4 (273 aa)    
Predicted Functional Partners:
MYADML2
Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2 (307 aa)
      
   
  0.812
PAQR9
Membrane progestin receptor epsilon; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. May be involved in regulating rapid P4 signaling in the nervous system. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone; Progestin and adipoQ receptor family (377 aa)
            
  0.722
STX1B
Syntaxin-1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity); Belongs to the syntaxin family (288 aa)
            
  0.682
PAQR6
Membrane progestin receptor delta; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. Involved in neurosteroid inhibition of apoptosis. May be involved in regulating rapid P4 signaling in the nervous system. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone; Belongs to the ADIPOR family (351 aa)
      
   
  0.553
PAQR7
Membrane progestin receptor alpha; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation. Involved in neurosteroid inhibition of apoptosis. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone; Belongs to the ADIPOR family (346 aa)
      
   
  0.552
RPL26L1
Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family (145 aa)
      
   
  0.544
ASB2
Ankyrin repeat and SOCS box protein 2; Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family (635 aa)
        
 
  0.541
KIAA1586
E3 SUMO-protein ligase KIAA1586; E3 SUMO-protein ligase; facilitates UBE2I/UBC9-mediated SUMO2 modification of target proteins (787 aa)
            
  0.536
KBTBD2
Kelch repeat and BTB domain containing 2 (623 aa)
            
  0.517
FLYWCH1
FLYWCH-type zinc finger 1 (715 aa)
            
  0.517
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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