• Version:
  • 11.0 [archived version]
STRINGSTRING
PROCA1 PROCA1 SPSB3 SPSB3 NEURL1B NEURL1B KLHDC1 KLHDC1 ANKRD29 ANKRD29 ACTR6 ACTR6 KLHL38 KLHL38 DUSP27 DUSP27 TRIM55 TRIM55 COL9A1 COL9A1 DUPD1 DUPD1
"KLHL38" - Kelch-like protein 38 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL38Kelch-like protein 38; Kelch like family member 38; BTB domain containing (581 aa)    
Predicted Functional Partners:
NEURL1B
E3 ubiquitin-protein ligase NEURL1B; E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands; Ring finger proteins (555 aa)
           
  0.758
DUSP27
Inactive dual specificity phosphatase 27; May be required for myofiber maturation (1158 aa)
     
   
  0.752
DUPD1
Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate (220 aa)
     
   
  0.715
ACTR6
ARP6 actin related protein 6 homolog; Belongs to the actin family. ARP6 subfamily (396 aa)
     
   
  0.688
COL9A1
Collagen alpha-1(IX) chain; Structural component of hyaline cartilage and vitreous of the eye; Collagen proteoglycans (921 aa)
           
  0.631
SPSB3
SPRY domain-containing SOCS box protein 3; May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (355 aa)
           
  0.548
TRIM55
Tripartite motif-containing protein 55; May regulate gene expression and protein turnover in muscle cells; Ring finger proteins (548 aa)
     
   
  0.545
ANKRD29
Ankyrin repeat domain-containing protein 29; Ankyrin repeat domain containing (301 aa)
           
  0.533
PROCA1
Protein interacting with cyclin A1; Belongs to the PROCA1 family (336 aa)
           
  0.522
KLHDC1
Kelch domain containing 1 (406 aa)
     
   
  0.518
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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