VCX2 protein (human) - STRING database

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VCX2

Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family (139 aa)

Predicted Functional Partners:

HDHD1

0.688

IL1RAPL1

0.643

CLCN4

0.640

ARX

0.640

PNPLA4

0.630

OR10G9

0.558

OR8D1

0.558

STS

0.556

CT45A10

0.524

CT45-5

0.523

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARX	CLCN4	ENSP00000368332	ENSP00000370213	Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily	H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons; Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily	0.657
ARX	IL1RAPL1	ENSP00000368332	ENSP00000368278	Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family	0.664
ARX	VCX2	ENSP00000368332	ENSP00000321309	Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.640
CLCN4	ARX	ENSP00000370213	ENSP00000368332	H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons; Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily	Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily	0.657
CLCN4	IL1RAPL1	ENSP00000370213	ENSP00000368278	H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons; Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family	0.694
CLCN4	STS	ENSP00000370213	ENSP00000217961	H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons; Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily	Steryl-sulfatase; Conversion of sulfated steroid precursors to estrogens during pregnancy; Sulfatases	0.532
CLCN4	VCX2	ENSP00000370213	ENSP00000321309	H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons; Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.640
CT45-5	VCX2	ENSP00000482241	ENSP00000321309	annotation not available	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.523
CT45A10	VCX2	ENSP00000484601	ENSP00000321309	Cancer/testis antigen family 45 member A5	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.524
HDHD1	PNPLA4	ENSP00000396452	ENSP00000370430	Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family	Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase; Patatin like phospholipase domain containing	0.882
HDHD1	STS	ENSP00000396452	ENSP00000217961	Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family	Steryl-sulfatase; Conversion of sulfated steroid precursors to estrogens during pregnancy; Sulfatases	0.651
HDHD1	VCX2	ENSP00000396452	ENSP00000321309	Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.688
IL1RAPL1	ARX	ENSP00000368278	ENSP00000368332	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family	Homeobox protein ARX; Transcription factor required for normal brain development. May be important for maintenance of specific neuronal subtypes in the cerebral cortex and axonal guidance in the floor plate; Belongs to the paired homeobox family. Bicoid subfamily	0.664
IL1RAPL1	CLCN4	ENSP00000368278	ENSP00000370213	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family	H(+)/Cl(-) exchange transporter 4; Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons; Belongs to the chloride channel (TC 2.A.49) family. ClC-4/CLCN4 subfamily	0.694
IL1RAPL1	VCX2	ENSP00000368278	ENSP00000321309	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK. Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans- synaptically binding to PTPRD (By similarity); Belongs to the interleukin-1 receptor family	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.643
OR10G9	VCX2	ENSP00000364164	ENSP00000321309	Olfactory receptor 10G9; Odorant receptor; Olfactory receptors, family 10	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.558
OR8D1	VCX2	ENSP00000350474	ENSP00000321309	Olfactory receptor 8D1; Odorant receptor (Potential). May be involved in taste perception; Olfactory receptors, family 8	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.558
PNPLA4	HDHD1	ENSP00000370430	ENSP00000396452	Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase; Patatin like phospholipase domain containing	Pseudouridine-5’-phosphatase; Dephosphorylates pseudouridine 5’-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine; Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family	0.882
PNPLA4	STS	ENSP00000370430	ENSP00000217961	Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase; Patatin like phospholipase domain containing	Steryl-sulfatase; Conversion of sulfated steroid precursors to estrogens during pregnancy; Sulfatases	0.445
PNPLA4	VCX2	ENSP00000370430	ENSP00000321309	Patatin-like phospholipase domain-containing protein 4; Lipid hydrolase; Patatin like phospholipase domain containing	Variable charge X-linked protein 2; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Variable charge X/Y family	0.630

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