node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADK | PITPNB | ENSP00000286621 | ENSP00000321266 | Adenosine kinase; ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides; Belongs to the carbohydrate kinase PfkB family | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | 0.683 |
ESD | MPI | ENSP00000367992 | ENSP00000318318 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde | Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the mannose-6-phosphate isomerase type 1 family | 0.467 |
ESD | OAT | ENSP00000367992 | ENSP00000357838 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase | 0.494 |
ESD | PITPNB | ENSP00000367992 | ENSP00000321266 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | 0.704 |
ESD | SLC35F6 | ENSP00000367992 | ENSP00000345528 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde | Solute carrier family 35 member F6; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | 0.562 |
MPI | ESD | ENSP00000318318 | ENSP00000367992 | Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the mannose-6-phosphate isomerase type 1 family | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde | 0.467 |
MPI | PITPNB | ENSP00000318318 | ENSP00000321266 | Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the mannose-6-phosphate isomerase type 1 family | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | 0.810 |
MPI | TIA1 | ENSP00000318318 | ENSP00000401371 | Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the mannose-6-phosphate isomerase type 1 family | Nucleolysin TIA-1 isoform p40; Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3’ untranslated regions (3’ UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis | 0.856 |
OAT | ESD | ENSP00000357838 | ENSP00000367992 | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde | 0.494 |
OAT | PITPNB | ENSP00000357838 | ENSP00000321266 | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | 0.822 |
PITPNB | ADK | ENSP00000321266 | ENSP00000286621 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | Adenosine kinase; ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides; Belongs to the carbohydrate kinase PfkB family | 0.683 |
PITPNB | ESD | ENSP00000321266 | ENSP00000367992 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde | 0.704 |
PITPNB | MPI | ENSP00000321266 | ENSP00000318318 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | Mannose-6-phosphate isomerase; Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions; Belongs to the mannose-6-phosphate isomerase type 1 family | 0.810 |
PITPNB | OAT | ENSP00000321266 | ENSP00000357838 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | Ornithine aminotransferase, mitochondrial; Ornithine aminotransferase | 0.822 |
PITPNB | SEC14L2 | ENSP00000321266 | ENSP00000478755 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | SEC14-like protein 2; Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell; SEC14 family | 0.647 |
PITPNB | SEC14L3 | ENSP00000321266 | ENSP00000215812 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | SEC14-like protein 3; Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids; SEC14 family | 0.673 |
PITPNB | SEC14L5 | ENSP00000321266 | ENSP00000251170 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | SEC14-like protein 5; SEC14 like lipid binding 5; PRELI domain containing | 0.606 |
PITPNB | SEC14L6 | ENSP00000321266 | ENSP00000385695 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | Putative SEC14-like protein 6; SEC14 like lipid binding 6 | 0.705 |
PITPNB | SLC35F6 | ENSP00000321266 | ENSP00000345528 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | Solute carrier family 35 member F6; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | 0.628 |
PITPNB | TIA1 | ENSP00000321266 | ENSP00000401371 | Phosphatidylinositol transfer protein beta isoform; Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes; Phosphatidylinositol transfer proteins | Nucleolysin TIA-1 isoform p40; Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3’ untranslated regions (3’ UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis | 0.812 |