• Version:
  • 11.0 [archived version]
STRINGSTRING
BICD1 BICD1 FAR2 FAR2 PDZRN4 PDZRN4 CCDC91 CCDC91 CCDC184 CCDC184 PCDHA11 PCDHA11 SLC2A13 SLC2A13 CCDC85A CCDC85A SNX16 SNX16 CCDC85C CCDC85C CCDC85B CCDC85B
"CCDC184" - Coiled-coil domain containing 184 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurence
Coexpression
Experiments
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[Homology]
Score
CCDC184Coiled-coil domain containing 184 (194 aa)    
Predicted Functional Partners:
PCDHA11
Protocadherin alpha-11; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (949 aa)
     
   
  0.641
CCDC85C
Coiled-coil domain-containing protein 85C; May play an important role in cortical development, especially in the maintenance of radial glia (419 aa)
           
  0.617
CCDC85A
Coiled-coil domain containing 85A; Belongs to the CCDC85 family (553 aa)
     
   
  0.597
PDZRN4
PDZ domain containing ring finger 4 (1036 aa)
     
   
  0.561
CCDC91
Coiled-coil domain-containing protein 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes (441 aa)
           
  0.510
SNX16
Sorting nexin-16; May be involved in several stages of intracellular trafficking. Plays a role in protein transport from early to late endosomes. Plays a role in protein transport to the lysosome. Promotes degradation of EGFR after EGF signaling. Plays a role in intracellular transport of vesicular stomatitis virus nucleocapsids from the endosome to the cytoplasm; Belongs to the sorting nexin family (344 aa)
           
  0.502
CCDC85B
Coiled-coil domain-containing protein 85B; Functions as a transcriptional repressor. May inhibit the activity of CTNNB1 in a TP53- dependent manner and thus regulate cell growth. May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity) (202 aa)
           
  0.481
FAR2
Fatty acyl-CoA reductase 2; Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. A lower activity can be observed with shorter fatty acyl-CoA substrates. It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates (By similarity) (515 aa)
           
  0.473
SLC2A13
Proton myo-inositol cotransporter; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family (648 aa)
           
  0.445
BICD1
Protein bicaudal D homolog 1; Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex; Belongs to the BicD family (975 aa)
           
  0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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