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  • 11.0 [archived version]
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NADK2 NADK2 SH3D21 SH3D21 RPS28 RPS28 SLC24A4 SLC24A4 RAB30 RAB30 GDPD4 GDPD4 KIAA1919 KIAA1919 AQP11 AQP11 FAM228A FAM228A MECR MECR CCDC6 CCDC6
"GDPD4" - Glycerophosphodiester phosphodiesterase domain containing 4 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GDPD4Glycerophosphodiester phosphodiesterase domain containing 4; Belongs to the glycerophosphoryl diester phosphodiesterase family (520 aa)    
Predicted Functional Partners:
MECR
Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Has a preference for short and medium chain substrates, including trans-2-hexenoyl-CoA (C6), trans-2-decenoyl-CoA (C10), and trans- 2-hexadecenoyl-CoA (C16) (373 aa)
     
   
  0.759
RAB30
Ras-related protein Rab-30; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins; RAB, member RAS oncog [...] (203 aa)
           
  0.721
RPS28
Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family (69 aa)
           
  0.693
AQP11
Aquaporin-11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes (271 aa)
           
  0.659
FAM228A
Protein FAM228A; Family with sequence similarity 228 member A; Belongs to the FAM228 family (206 aa)
           
  0.557
SH3D21
SH3 domain containing 21 (645 aa)
           
  0.527
KIAA1919
Sodium-dependent glucose transporter 1; May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney (518 aa)
           
  0.513
NADK2
NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo (442 aa)
           
  0.473
CCDC6
Coiled-coil domain containing 6 (474 aa)
           
  0.473
SLC24A4
Sodium/potassium/calcium exchanger 4; Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived. May play a role in calcium transport during amelogenesis (By similarity); Belongs to the Ca(2+)-cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily (622 aa)
   
   
  0.455
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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