node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DIRAS3 | NAP1L5 | ENSP00000360020 | ENSP00000320488 | GTP-binding protein Di-Ras3; RAS type GTPase family | Nucleosome assembly protein 1 like 5 | 0.647 |
DIRAS3 | NNAT | ENSP00000360020 | ENSP00000062104 | GTP-binding protein Di-Ras3; RAS type GTPase family | Neuronatin; May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels | 0.534 |
DIRAS3 | PEG10 | ENSP00000360020 | ENSP00000418944 | GTP-binding protein Di-Ras3; RAS type GTPase family | Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...] | 0.525 |
DIRAS3 | PHLDA2 | ENSP00000360020 | ENSP00000319231 | GTP-binding protein Di-Ras3; RAS type GTPase family | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity); Belongs to the PHLDA2 family | 0.537 |
DIRAS3 | PLAGL1 | ENSP00000360020 | ENSP00000353734 | GTP-binding protein Di-Ras3; RAS type GTPase family | Zinc finger protein PLAGL1; Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.654 |
DIRAS3 | SNRPN | ENSP00000360020 | ENSP00000382972 | GTP-binding protein Di-Ras3; RAS type GTPase family | Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events; Sm spliceosomal proteins | 0.485 |
KAT5 | NAP1L5 | ENSP00000340330 | ENSP00000320488 | Histone acetyltransferase KAT5; Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replica [...] | Nucleosome assembly protein 1 like 5 | 0.665 |
NAP1L5 | DIRAS3 | ENSP00000320488 | ENSP00000360020 | Nucleosome assembly protein 1 like 5 | GTP-binding protein Di-Ras3; RAS type GTPase family | 0.647 |
NAP1L5 | KAT5 | ENSP00000320488 | ENSP00000340330 | Nucleosome assembly protein 1 like 5 | Histone acetyltransferase KAT5; Catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replica [...] | 0.665 |
NAP1L5 | NNAT | ENSP00000320488 | ENSP00000062104 | Nucleosome assembly protein 1 like 5 | Neuronatin; May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels | 0.748 |
NAP1L5 | NOL6 | ENSP00000320488 | ENSP00000297990 | Nucleosome assembly protein 1 like 5 | Nucleolar protein 6; Belongs to the NRAP family | 0.798 |
NAP1L5 | PEG10 | ENSP00000320488 | ENSP00000418944 | Nucleosome assembly protein 1 like 5 | Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...] | 0.732 |
NAP1L5 | PHLDA2 | ENSP00000320488 | ENSP00000319231 | Nucleosome assembly protein 1 like 5 | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity); Belongs to the PHLDA2 family | 0.699 |
NAP1L5 | PLAGL1 | ENSP00000320488 | ENSP00000353734 | Nucleosome assembly protein 1 like 5 | Zinc finger protein PLAGL1; Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.643 |
NAP1L5 | PPP1R9A | ENSP00000320488 | ENSP00000405514 | Nucleosome assembly protein 1 like 5 | Neurabin-1; Binds to actin filaments (F-actin) and shows cross- linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1- alpha activity (By similarity); PDZ domain containing | 0.706 |
NAP1L5 | SNRPN | ENSP00000320488 | ENSP00000382972 | Nucleosome assembly protein 1 like 5 | Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events; Sm spliceosomal proteins | 0.648 |
NAP1L5 | ZRSR1 | ENSP00000320488 | ENSP00000375133 | Nucleosome assembly protein 1 like 5 | U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1; Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 | 0.740 |
NNAT | DIRAS3 | ENSP00000062104 | ENSP00000360020 | Neuronatin; May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels | GTP-binding protein Di-Ras3; RAS type GTPase family | 0.534 |
NNAT | NAP1L5 | ENSP00000062104 | ENSP00000320488 | Neuronatin; May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels | Nucleosome assembly protein 1 like 5 | 0.748 |
NNAT | PEG10 | ENSP00000062104 | ENSP00000418944 | Neuronatin; May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels | Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5’-GCCTGTCTTT-3’ DNA sequence of the MB1 domain in the myelin basic protein (M [...] | 0.718 |