node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AVPR2 | ZFP3 | ENSP00000351805 | ENSP00000320347 | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.631 |
ENSG00000276760 | ZFP3 | ENSP00000478796 | ENSP00000320347 | POTE ankyrin domain family member B | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.489 |
IDH1 | TP53 | ENSP00000390265 | ENSP00000269305 | Isocitrate dehydrogenase 1, cytosolic | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in [...] | 0.770 |
IDH1 | ZFP3 | ENSP00000390265 | ENSP00000320347 | Isocitrate dehydrogenase 1, cytosolic | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.504 |
POLR2L | ZFP3 | ENSP00000324124 | ENSP00000320347 | DNA-directed RNA polymerases I, II, and III subunit RPABC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of t [...] | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.494 |
POTEB2 | ZFP3 | ENSP00000456953 | ENSP00000320347 | POTE ankyrin domain family member B2; Belongs to the POTE family | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.507 |
RCVRN | ZFP3 | ENSP00000226193 | ENSP00000320347 | Recoverin; Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse; EF-hand domain containing | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.643 |
RNF113B | ZFP3 | ENSP00000267291 | ENSP00000320347 | Ring finger protein 113B | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.494 |
SPARC | TP53 | ENSP00000231061 | ENSP00000269305 | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity; SPARC family | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in [...] | 0.412 |
SPARC | ZFP3 | ENSP00000231061 | ENSP00000320347 | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity; SPARC family | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.518 |
TP53 | IDH1 | ENSP00000269305 | ENSP00000390265 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in [...] | Isocitrate dehydrogenase 1, cytosolic | 0.770 |
TP53 | SPARC | ENSP00000269305 | ENSP00000231061 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in [...] | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity; SPARC family | 0.412 |
TP53 | ZFP3 | ENSP00000269305 | ENSP00000320347 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in [...] | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.507 |
TUBA3E | ZFP3 | ENSP00000318197 | ENSP00000320347 | Tubulin alpha-3E chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity); Belongs to the tubulin family | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.891 |
ZFP3 | AVPR2 | ENSP00000320347 | ENSP00000351805 | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Vasopressin V2 receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily | 0.631 |
ZFP3 | ENSG00000276760 | ENSP00000320347 | ENSP00000478796 | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | POTE ankyrin domain family member B | 0.489 |
ZFP3 | IDH1 | ENSP00000320347 | ENSP00000390265 | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Isocitrate dehydrogenase 1, cytosolic | 0.504 |
ZFP3 | POLR2L | ENSP00000320347 | ENSP00000324124 | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | DNA-directed RNA polymerases I, II, and III subunit RPABC5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of t [...] | 0.494 |
ZFP3 | POTEB2 | ENSP00000320347 | ENSP00000456953 | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | POTE ankyrin domain family member B2; Belongs to the POTE family | 0.507 |
ZFP3 | RCVRN | ENSP00000320347 | ENSP00000226193 | Zinc finger protein 3 homolog; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Recoverin; Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse; EF-hand domain containing | 0.643 |