| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASCC2 | ITFG1 | ENSP00000380877 | ENSP00000319918 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | 0.583 |
| ASCC2 | KIAA1715 | ENSP00000380877 | ENSP00000272748 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb and central nervous system development (By similarity) | 0.591 |
| ASCC2 | RFX7 | ENSP00000380877 | ENSP00000453281 | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | DNA-binding protein RFX7; Regulatory factor X family; Belongs to the RFX family | 0.435 |
| ATP9A | ITFG1 | ENSP00000342481 | ENSP00000319918 | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | 0.636 |
| ATP9B | ITFG1 | ENSP00000398076 | ENSP00000319918 | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | 0.636 |
| ITFG1 | ASCC2 | ENSP00000319918 | ENSP00000380877 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | 0.583 |
| ITFG1 | ATP9A | ENSP00000319918 | ENSP00000342481 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Probable phospholipid-transporting ATPase IIA; ATPase phospholipid transporting 9A | 0.636 |
| ITFG1 | ATP9B | ENSP00000319918 | ENSP00000398076 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Probable phospholipid-transporting ATPase IIB; ATPase phospholipid transporting 9B | 0.636 |
| ITFG1 | KIAA1715 | ENSP00000319918 | ENSP00000272748 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb and central nervous system development (By similarity) | 0.714 |
| ITFG1 | PRPSAP2 | ENSP00000319918 | ENSP00000268835 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Phosphoribosyl pyrophosphate synthase-associated protein 2; Seems to play a negative regulatory role in 5- phosphoribose 1-diphosphate synthesis | 0.555 |
| ITFG1 | RFX7 | ENSP00000319918 | ENSP00000453281 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | DNA-binding protein RFX7; Regulatory factor X family; Belongs to the RFX family | 0.546 |
| ITFG1 | RUVBL1 | ENSP00000319918 | ENSP00000318297 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | RuvB-like 1; May be able to bind plasminogen at cell surface and enhance plasminogen activation; AAA ATPases | 0.631 |
| ITFG1 | RUVBL2 | ENSP00000319918 | ENSP00000473172 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | RuvB-like 2; Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway where it negatively regulates expression of ER stress response genes; Belongs to the RuvB family | 0.582 |
| ITFG1 | TIPIN | ENSP00000319918 | ENSP00000261881 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic st [...] | 0.768 |
| ITFG1 | TM7SF3 | ENSP00000319918 | ENSP00000342322 | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | Transmembrane 7 superfamily member 3; Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells. Is a downstream transcriptional target of p53/TP53, and acts as a pro- survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR) | 0.664 |
| KIAA1715 | ASCC2 | ENSP00000272748 | ENSP00000380877 | Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb and central nervous system development (By similarity) | Activating signal cointegrator 1 complex subunit 2; Enhances NF-kappa-B, SRF and AP1 transactivation | 0.591 |
| KIAA1715 | ITFG1 | ENSP00000272748 | ENSP00000319918 | Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb and central nervous system development (By similarity) | T-cell immunomodulatory protein; Modulator of T-cell function. Has a protective effect in graft versus host disease model (By similarity); Belongs to the TIP family | 0.714 |
| KIAA1715 | PRPSAP2 | ENSP00000272748 | ENSP00000268835 | Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb and central nervous system development (By similarity) | Phosphoribosyl pyrophosphate synthase-associated protein 2; Seems to play a negative regulatory role in 5- phosphoribose 1-diphosphate synthesis | 0.563 |
| KIAA1715 | RFX7 | ENSP00000272748 | ENSP00000453281 | Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb and central nervous system development (By similarity) | DNA-binding protein RFX7; Regulatory factor X family; Belongs to the RFX family | 0.560 |
| KIAA1715 | TM7SF3 | ENSP00000272748 | ENSP00000342322 | Endoplasmic reticulum junction formation protein lunapark; Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology. Involved in the stabilization of nascent three-way ER tubular junctions within the ER network. May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network. May be involved in limb and central nervous system development (By similarity) | Transmembrane 7 superfamily member 3; Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells. Is a downstream transcriptional target of p53/TP53, and acts as a pro- survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR) | 0.635 |
