node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHP1 | RCN2 | ENSP00000335632 | ENSP00000319739 | Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...] | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | 0.690 |
CHP1 | SFXN1 | ENSP00000335632 | ENSP00000316905 | Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...] | Sideroflexin-1; Might be involved in the transport of a component required for iron utilization into or out of the mitochondria; Sideroflexins | 0.402 |
CHP1 | TMBIM4 | ENSP00000335632 | ENSP00000286424 | Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...] | Transmembrane BAX inhibitor motif containing 4; Belongs to the BI1 family | 0.616 |
KDELR1 | RCN2 | ENSP00000329471 | ENSP00000319739 | ER lumen protein-retaining receptor 1; Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | 0.768 |
NPTX1 | NPTXR | ENSP00000307549 | ENSP00000327545 | Neuronal pentraxin-1; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | 0.542 |
NPTX1 | RCN2 | ENSP00000307549 | ENSP00000319739 | Neuronal pentraxin-1; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | 0.817 |
NPTX2 | NPTXR | ENSP00000265634 | ENSP00000327545 | Neuronal pentraxin-2; Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity) | Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | 0.453 |
NPTX2 | RCN2 | ENSP00000265634 | ENSP00000319739 | Neuronal pentraxin-2; Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity) | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | 0.710 |
NPTXR | NPTX1 | ENSP00000327545 | ENSP00000307549 | Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | Neuronal pentraxin-1; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | 0.542 |
NPTXR | NPTX2 | ENSP00000327545 | ENSP00000265634 | Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | Neuronal pentraxin-2; Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity) | 0.453 |
NPTXR | RCN2 | ENSP00000327545 | ENSP00000319739 | Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | 0.804 |
PIGX | RCN2 | ENSP00000296333 | ENSP00000319739 | Phosphatidylinositol-glycan biosynthesis class X protein; Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity); Belongs to the PIGX family | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | 0.831 |
RCN2 | CHP1 | ENSP00000319739 | ENSP00000335632 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...] | 0.690 |
RCN2 | KDELR1 | ENSP00000319739 | ENSP00000329471 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | ER lumen protein-retaining receptor 1; Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi | 0.768 |
RCN2 | NPTX1 | ENSP00000319739 | ENSP00000307549 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | Neuronal pentraxin-1; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | 0.817 |
RCN2 | NPTX2 | ENSP00000319739 | ENSP00000265634 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | Neuronal pentraxin-2; Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity) | 0.710 |
RCN2 | NPTXR | ENSP00000319739 | ENSP00000327545 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | Neuronal pentraxin receptor; May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses; Long pentraxins | 0.804 |
RCN2 | PIGX | ENSP00000319739 | ENSP00000296333 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | Phosphatidylinositol-glycan biosynthesis class X protein; Essential component of glycosylphosphatidylinositol- mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity); Belongs to the PIGX family | 0.831 |
RCN2 | SFXN1 | ENSP00000319739 | ENSP00000316905 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | Sideroflexin-1; Might be involved in the transport of a component required for iron utilization into or out of the mitochondria; Sideroflexins | 0.812 |
RCN2 | SIPA1L1 | ENSP00000319739 | ENSP00000450832 | Reticulocalbin-2; Not known. Binds calcium; EF-hand domain containing | Signal-induced proliferation-associated 1-like protein 1; Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F- actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity); PDZ domain containing | 0.677 |