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  • 11.0 [archived version]
STRINGSTRING
S100PBP S100PBP HENMT1 HENMT1 EFCAB6 EFCAB6 FLYWCH2 FLYWCH2 FAM86C1 FAM86C1 ZNF720 ZNF720 C16orf52 C16orf52 WDR90 WDR90 RSC1A1 RSC1A1 TRIM28 TRIM28 ERI2 ERI2
"ZNF720" - Putative protein ZNF720 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF720Putative protein ZNF720; Zinc finger protein 720; Zinc fingers C2H2-type (126 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.924
FLYWCH2
FLYWCH family member 2 (140 aa)
           
  0.634
C16orf52
Uncharacterized protein C16orf52; Chromosome 16 open reading frame 52 (167 aa)
           
  0.630
WDR90
WD repeat-containing protein 90; WD repeat domain containing (1748 aa)
     
 
  0.570
RSC1A1
Regulatory solute carrier protein family 1 member 1; Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network (617 aa)
     
 
  0.557
FAM86C1
Protein FAM86C1; Family with sequence similarity 86 member C1 (165 aa)
           
  0.556
EFCAB6
EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex; EF-hand domain containing (1501 aa)
       
 
  0.549
S100PBP
S100P binding protein (408 aa)
           
  0.480
HENMT1
Small RNA 2’-O-methyltransferase; Methyltransferase that adds a 2’-O-methyl group at the 3’-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3’-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis; Seven-beta-strand methyltransferase motif containing (393 aa)
           
  0.478
ERI2
ERI1 exoribonuclease family member 2; Belongs to the ERI2 family (691 aa)
       
 
  0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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