• Version:
  • 11.0 [archived version]
STRINGSTRING
CT45A4 CT45A4 CT45A1 CT45A1 RNF151 RNF151 C11orf57 C11orf57 ENSG00000278289 ENSG00000278289 RBMX2 RBMX2 FAM133A FAM133A C1orf35 C1orf35 FAM46D FAM46D H2AFY2 H2AFY2 HIST1H2BN HIST1H2BN
"FAM133A" - Protein FAM133A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM133AProtein FAM133A; Family with sequence similarity 133 member A (248 aa)    
Predicted Functional Partners:
RBMX2
RNA binding motif protein, X-linked 2 (322 aa)
      
      0.818
H2AFY2
Core histone macro-H2A.2; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inac [...] (372 aa)
        
      0.793
RNF151
RING finger protein 151; May be involved in acrosome formation of spermatids; Ring finger proteins (245 aa)
        
      0.738
HIST1H2BN
Histone H2B type 1-N; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (126 aa)
        
      0.728
CT45A1
Cancer/testis antigen family 45 member A1; Belongs to the CT45 family (189 aa)
      
 
  0.714
C11orf57
Uncharacterized protein NKAPD1; Chromosome 11 open reading frame 57 (293 aa)
        
      0.694
C1orf35
Multiple myeloma tumor-associated protein 2; Chromosome 1 open reading frame 35 (263 aa)
        
      0.689
FAM46D
Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase (389 aa)
      
   
  0.686
ENSG00000278289
Cancer/testis antigen family 45 member A6 (189 aa)
      
   
  0.642
CT45A4
Cancer/testis antigen family 45 member A3 (189 aa)
      
   
  0.589
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]
STRING is part of the ELIXIR infrastructure: it is one of ELIXIR's Core Data Resources.  Learn more >