| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMPH | ARHGAP26 | ENSP00000348602 | ENSP00000274498 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | 0.671 |
| AMPH | ATP1A3 | ENSP00000348602 | ENSP00000444688 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | Sodium/potassium-transporting ATPase subunit alpha-3; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily | 0.402 |
| AMPH | DNER | ENSP00000348602 | ENSP00000345229 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | Delta and Notch-like epidermal growth factor-related receptor; Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity) | 0.771 |
| AMPH | DPP6 | ENSP00000348602 | ENSP00000367001 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity; DASH family | 0.669 |
| AMPH | LGI1 | ENSP00000348602 | ENSP00000360472 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | Leucine-rich glioma-inactivated protein 1; Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival | 0.741 |
| AMPH | PNMA1 | ENSP00000348602 | ENSP00000318914 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | Paraneoplastic Ma antigens; Belongs to the PNMA family | 0.539 |
| AMPH | ZIC4 | ENSP00000348602 | ENSP00000435509 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | Zinc finger protein ZIC 4; Binds to DNA; Zinc fingers C2H2-type | 0.793 |
| ARHGAP26 | AMPH | ENSP00000274498 | ENSP00000348602 | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | 0.671 |
| ARHGAP26 | DNER | ENSP00000274498 | ENSP00000345229 | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | Delta and Notch-like epidermal growth factor-related receptor; Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity) | 0.813 |
| ARHGAP26 | DPP6 | ENSP00000274498 | ENSP00000367001 | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity; DASH family | 0.682 |
| ARHGAP26 | LGI1 | ENSP00000274498 | ENSP00000360472 | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | Leucine-rich glioma-inactivated protein 1; Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival | 0.672 |
| ARHGAP26 | PNMA1 | ENSP00000274498 | ENSP00000318914 | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | Paraneoplastic Ma antigens; Belongs to the PNMA family | 0.639 |
| ARHGAP26 | ZIC4 | ENSP00000274498 | ENSP00000435509 | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | Zinc finger protein ZIC 4; Binds to DNA; Zinc fingers C2H2-type | 0.761 |
| ATP1A3 | AMPH | ENSP00000444688 | ENSP00000348602 | Sodium/potassium-transporting ATPase subunit alpha-3; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | 0.402 |
| ATP1A3 | DNER | ENSP00000444688 | ENSP00000345229 | Sodium/potassium-transporting ATPase subunit alpha-3; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily | Delta and Notch-like epidermal growth factor-related receptor; Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity) | 0.444 |
| ATP1A3 | PNMA1 | ENSP00000444688 | ENSP00000318914 | Sodium/potassium-transporting ATPase subunit alpha-3; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily | Paraneoplastic Ma antigens; Belongs to the PNMA family | 0.559 |
| ATP1A3 | ZIC4 | ENSP00000444688 | ENSP00000435509 | Sodium/potassium-transporting ATPase subunit alpha-3; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily | Zinc finger protein ZIC 4; Binds to DNA; Zinc fingers C2H2-type | 0.447 |
| DNER | AMPH | ENSP00000345229 | ENSP00000348602 | Delta and Notch-like epidermal growth factor-related receptor; Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity) | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton; N-BAR domain containing | 0.771 |
| DNER | ARHGAP26 | ENSP00000345229 | ENSP00000274498 | Delta and Notch-like epidermal growth factor-related receptor; Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity) | Rho GTPase-activating protein 26; GTPase-activating protein for RHOA and CDC42 | 0.813 |
| DNER | ATP1A3 | ENSP00000345229 | ENSP00000444688 | Delta and Notch-like epidermal growth factor-related receptor; Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis (By similarity) | Sodium/potassium-transporting ATPase subunit alpha-3; This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily | 0.444 |
