• Version:
  • 11.0 [archived version]
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OPN1SW OPN1SW RBP3 RBP3 PRCD PRCD SNX19 SNX19 ZNF513 ZNF513 IMPG2 IMPG2 FAM161A FAM161A TTC8 TTC8 CLRN1 CLRN1 C2orf71 C2orf71 RP1L1 RP1L1
"ZNF513" - Zinc finger protein 513 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ZNF513Zinc finger protein 513; Transcriptional regulator that plays a role in retinal development and maintenance; Zinc fingers C2H2-type (541 aa)    
Predicted Functional Partners:
SNX19
Sorting nexin-19; Plays a role in intracellular vesicle trafficking and exocytosis. May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation. May play a role in insulin secretion. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity); Belongs to the sorting nexin family (992 aa)
           
  0.706
FAM161A
Protein FAM161A; Involved in ciliogenesis (716 aa)
           
  0.671
C2orf71
Uncharacterized protein C2orf71; May play an important role in the development of normal vision (1288 aa)
           
  0.670
IMPG2
Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light- sensitive photoreceptor outer segment. Binds heparin (1241 aa)
           
  0.670
RP1L1
Retinitis pigmentosa 1-like 1 protein; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity); Doublecortin superfamily (2400 aa)
           
  0.668
TTC8
Tetratricopeptide repeat protein 8; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl [...] (531 aa)
       
 
  0.656
PRCD
Progressive rod-cone degeneration protein; Involved in vision (54 aa)
           
  0.654
OPN1SW
Short-wave-sensitive opsin 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily (348 aa)
       
 
  0.653
RBP3
Retinol-binding protein 3; IRBP shuttles 11-cis and all trans retinoids between the retinol isomerase in the pigment epithelium and the visual pigments in the photoreceptor cells of the retina (1247 aa)
           
  0.640
CLRN1
Clarin-1; May have a role in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in analogous synapses within the retina; Belongs to the clarin family (245 aa)
           
  0.632
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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