• Version:
  • 11.0 [archived version]
STRINGSTRING
GRXCR2 GRXCR2 ELMO3 ELMO3 GLYATL3 GLYATL3 ELMOD1 ELMOD1 ELMOD3 ELMOD3 STPG1 STPG1 RETSAT RETSAT SH2D6 SH2D6 ASPRV1 ASPRV1 TMEM150A TMEM150A C2orf68 C2orf68
"ELMOD3" - ELMO domain-containing protein 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
ELMOD3ELMO domain-containing protein 3; Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity; Deafness associated genes (391 aa)    
Predicted Functional Partners:
SH2D6
SH2 domain containing 6 (175 aa)
           
  0.583
ELMOD1
ELMO domain-containing protein 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (334 aa)
           
  0.556
GLYATL3
Glycine N-acyltransferase-like protein 3; Acyltransferase which transfers the acyl group to the N- terminus of glycine (288 aa)
           
  0.536
ASPRV1
Retroviral-like aspartic protease 1; Gag like LTR retrotransposon derived genes (343 aa)
       
      0.519
C2orf68
UPF0561 protein C2orf68; Chromosome 2 open reading frame 68 (166 aa)
           
  0.499
TMEM150A
Transmembrane protein 150A; Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex. Acts as a regulator of phosphatidylinositol 4- phosphate (PtdIns(4)P) synthesis. May also play a role in fasting-induced catabolism (By similarity) (271 aa)
     
   
  0.489
GRXCR2
Glutaredoxin domain-containing cysteine-rich protein 2; Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection; Deafness associated genes (248 aa)
           
  0.473
STPG1
O(6)-methylguanine-induced apoptosis 2; May positively contribute to the induction of apoptosis triggered by O(6)-methylguanine (334 aa)
           
  0.472
RETSAT
All-trans-retinol 13,14-reductase; Catalyzes the saturation of all-trans-retinol to all- trans-13,14-dihydroretinol. Does not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A. Independently of retinol conversion, may regulate liver metabolism upstream of MLXIPL/ChREBP. May play a role in adipocyte differentiation; Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily (610 aa)
           
  0.472
ELMO3
Engulfment and cell motility protein 3; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity) (773 aa)
           
  0.452
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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