• Version:
  • 11.0 [archived version]
STRINGSTRING
ENSG00000271449 ENSG00000271449 MRPL4 MRPL4 PCDHB11 PCDHB11 ZNF175 ZNF175 CT45-2 CT45-2 MRFAP1L1 MRFAP1L1 MS4A3 MS4A3 TSNAX TSNAX MORF4L2 MORF4L2 MRFAP1 MRFAP1 MORF4L1 MORF4L1
"MRFAP1L1" - Morf4 family associated protein 1 like 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
MRFAP1L1Morf4 family associated protein 1 like 1 (127 aa)    
Predicted Functional Partners:
MORF4L2
Mortality factor 4-like protein 2; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative [...] (288 aa)
     
 
  0.843
MORF4L1
Mortality factor 4-like protein 1; Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and repl [...] (362 aa)
     
 
  0.780
MRFAP1
Morf4 family associated protein 1 (127 aa)
     
   
0.738
CT45-2
Cancer/testis antigen family 45 member A2 (189 aa)
           
  0.571
ENSG00000271449
Cancer/testis antigen family 45 member A2 (189 aa)
           
  0.571
PCDHB11
Protocadherin beta-11; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (797 aa)
           
  0.514
TSNAX
Translin-associated protein X; Acts in combination with TSN as an endonuclease involved in the activation of the RNA-induced silencing complex (RISC). Possible role in spermatogenesis (290 aa)
     
 
  0.500
ZNF175
Zinc finger protein 175; Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat- induced viral LTR promoter activity; Zinc fingers C2H2-type (711 aa)
           
  0.473
MRPL4
Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family (311 aa)
           
  0.473
MS4A3
Membrane-spanning 4-domains subfamily A member 3; Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP); Belongs to the MS4A family (214 aa)
           
  0.420
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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