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STRINGSTRING
LONRF2 LONRF2 MAP7D2 MAP7D2 PGBD5 PGBD5 MOAP1 MOAP1 PNMAL1 PNMAL1 RGAG1 RGAG1 RGAG4 RGAG4 PNMA1 PNMA1 LDOC1L LDOC1L ZCCHC12 ZCCHC12 ZCCHC5 ZCCHC5
"PNMAL1" - Paraneoplastic antigen-like protein 8A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
PNMAL1Paraneoplastic antigen-like protein 8A; Paraneoplastic Ma antigen family-like 1 (439 aa)    
Predicted Functional Partners:
MOAP1
Modulator of apoptosis 1; Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation; Belongs to the PNMA family (351 aa)
      
 
0.863
PNMA1
Paraneoplastic Ma antigens; Belongs to the PNMA family (353 aa)
      
 
0.847
RGAG1
Retrotransposon Gag-like protein 9; Retrotransposon gag domain containing 1 (1388 aa)
      
   
  0.769
RGAG4
Retrotransposon Gag-like protein 5; Retrotransposon gag domain containing 4 (569 aa)
      
   
  0.730
ZCCHC5
Retrotransposon Gag-like protein 3; May function as a transcriptional regulator. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (475 aa)
            
  0.712
LDOC1L
Retrotransposon Gag-like protein 6; Leucine zipper, down-regulated in cancer 1-like (239 aa)
      
   
  0.703
ZCCHC12
Zinc finger CCHC domain-containing protein 12; Transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression (By similarity); Paraneoplastic Ma antigens (402 aa)
      
   
  0.687
PGBD5
PiggyBac transposable element-derived protein 5; Transposase that mediates sequence-specific genomic rearrangements. Can induce genomic rearrangements that inactivate the HPRT1 gene; DNA transposon derived genes (455 aa)
      
   
  0.650
LONRF2
LON peptidase N-terminal domain and ring finger 2 (754 aa)
      
   
  0.637
MAP7D2
MAP7 domain containing 2 (773 aa)
      
   
  0.630
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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