• Version:
  • 11.0 [archived version]
STRINGSTRING
FAM114A1 FAM114A1 PHTF2 PHTF2 SLC2A9 SLC2A9 ZBTB26 ZBTB26 WDR1 WDR1 ZNF518B ZNF518B SLC25A15 SLC25A15 TBC1D9B TBC1D9B GNPNAT1 GNPNAT1 AMER3 AMER3 HLTF HLTF
"ZNF518B" - Zinc finger protein 518B in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF518BZinc finger protein 518B; May be involved in transcriptional regulation; Zinc fingers C2H2-type (1074 aa)    
Predicted Functional Partners:
GNPNAT1
Glucosamine-phosphate N-acetyltransferase 1; Belongs to the acetyltransferase family. GNA1 subfamily (184 aa)
       
 
  0.664
AMER3
APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) (861 aa)
           
  0.629
WDR1
WD repeat-containing protein 1; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing (By similarity). Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance (By similarity). Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape chan [...] (606 aa)
           
  0.557
SLC2A9
Solute carrier family 2, facilitated glucose transporter member 9; Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate; Solute carriers (540 aa)
     
   
  0.542
TBC1D9B
TBC1 domain family member 9B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing (1250 aa)
     
 
  0.533
SLC25A15
Mitochondrial ornithine transporter 1; Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix; Solute carriers (301 aa)
           
  0.522
ZBTB26
Zinc finger and BTB domain-containing protein 26; May be involved in transcriptional regulation; BTB domain containing (441 aa)
     
   
  0.513
HLTF
Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for ’Lys-63’-linked polyubiquitination of chromatin-bound PC [...] (1009 aa)
     
 
  0.500
PHTF2
Putative homeodomain transcription factor 2; May play a role in transcription regulation (751 aa)
           
  0.492
FAM114A1
Protein NOXP20; May play a role in neuronal cell development; Belongs to the FAM114 family (563 aa)
           
  0.490
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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