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STRINGSTRING
KAZN KAZN MVD MVD TAOK3 TAOK3 ZSWIM2 ZSWIM2 IFNGR1 IFNGR1 C16orf58 C16orf58 SLC5A2 SLC5A2 ZSCAN12 ZSCAN12 SEPHS2 SEPHS2 OR2B2 OR2B2 TBC1D10B TBC1D10B
"C16orf58" - RUS1 family protein C16orf58 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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C16orf58RUS1 family protein C16orf58; Chromosome 16 open reading frame 58; Belongs to the RUS1 family (468 aa)    
Predicted Functional Partners:
TBC1D10B
TBC1 domain family member 10B; Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A (808 aa)
            
  0.688
SEPHS2
Selenide, water dikinase 2; Synthesizes selenophosphate from selenide and ATP; Selenoproteins (483 aa)
      
   
  0.678
OR2B2
Olfactory receptor 2B2; Odorant receptor; Olfactory receptors, family 2 (357 aa)
            
  0.623
TAOK3
Serine/threonine-protein kinase TAO3; Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress- activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor (EGF) (898 aa)
            
  0.556
IFNGR1
Interferon gamma receptor 1; Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway; CD molecules (489 aa)
        
      0.551
ZSWIM2
E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins (633 aa)
            
  0.548
ZSCAN12
Zinc finger and SCAN domain-containing protein 12; May be involved in transcriptional regulation; SCAN domain containing (604 aa)
            
  0.524
MVD
Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes (400 aa)
  
 
        0.504
KAZN
Kazrin; Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known; Sterile alpha motif domain containing (775 aa)
            
  0.497
SLC5A2
Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1-1; Solute carriers (672 aa)
      
   
  0.479
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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