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  • 11.0 [archived version]
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ABHD12 ABHD12 TMEM246 TMEM246 PMFBP1 PMFBP1 GPLD1 GPLD1 TSEN15 TSEN15 ALPL ALPL NBPF3 NBPF3 HSD17B13 HSD17B13 NBPF1 NBPF1 TRIB1 TRIB1 COL22A1 COL22A1
"NBPF3" - Neuroblastoma breakpoint family member 3 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
NBPF3Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family (633 aa)    
Predicted Functional Partners:
ALPL
Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme may play a role in skeletal mineralization; Belongs to the alkaline phosphatase family (524 aa)
           
  0.800
NBPF1
Neuroblastoma breakpoint family member 1; NBPF member 1 (1139 aa)
     
 
0.708
TSEN15
tRNA-splicing endonuclease subunit Sen15; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA bo [...] (171 aa)
       
      0.547
PMFBP1
Polyamine-modulated factor 1-binding protein 1; May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular cytoskeleton (1007 aa)
           
  0.541
HSD17B13
17-beta-hydroxysteroid dehydrogenase 13; Short chain dehydrogenase/reductase superfamily (300 aa)
           
  0.514
TRIB1
Tribbles homolog 1; Adapter protein involved in protein degradation by interacting with RFWD2/COP1 ubiquitin ligase. The RFWD2-binding motif is masked by autoinhibitory interactions with the protein kinase domain. Serves to alter RFWD2 substrate specificity by directing the activity of RFWD2 toward CEBPA. Binds selectively the recognition sequence of CEBPA. Regulates myeloid cell differentiation by altering the expression of CEBPA in a RFWD2- dependent manner (By similarity). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity). Int [...] (372 aa)
           
  0.448
TMEM246
Transmembrane protein 246 (403 aa)
           
  0.445
ABHD12
Monoacylglycerol lipase ABHD12; Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways; Abhydrolase domain containing (404 aa)
           
  0.440
GPLD1
Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane (840 aa)
           
  0.430
COL22A1
Collagen alpha-1(XXII) chain; Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts; Belongs to the fibril-associated collagens with interrupted helices (FACIT) family (1626 aa)
           
  0.428
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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