node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABHD12 | NBPF3 | ENSP00000365725 | ENSP00000316782 | Monoacylglycerol lipase ABHD12; Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways; Abhydrolase domain containing | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | 0.440 |
ABHD12 | TMEM246 | ENSP00000365725 | ENSP00000363984 | Monoacylglycerol lipase ABHD12; Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways; Abhydrolase domain containing | Transmembrane protein 246 | 0.420 |
ALPL | GPLD1 | ENSP00000363973 | ENSP00000230036 | Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme may play a role in skeletal mineralization; Belongs to the alkaline phosphatase family | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane | 0.947 |
ALPL | NBPF3 | ENSP00000363973 | ENSP00000316782 | Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme may play a role in skeletal mineralization; Belongs to the alkaline phosphatase family | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | 0.800 |
COL22A1 | NBPF3 | ENSP00000303153 | ENSP00000316782 | Collagen alpha-1(XXII) chain; Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts; Belongs to the fibril-associated collagens with interrupted helices (FACIT) family | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | 0.428 |
GPLD1 | ALPL | ENSP00000230036 | ENSP00000363973 | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane | Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme may play a role in skeletal mineralization; Belongs to the alkaline phosphatase family | 0.947 |
GPLD1 | NBPF3 | ENSP00000230036 | ENSP00000316782 | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | 0.430 |
GPLD1 | TMEM246 | ENSP00000230036 | ENSP00000363984 | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane | Transmembrane protein 246 | 0.420 |
HSD17B13 | NBPF3 | ENSP00000333300 | ENSP00000316782 | 17-beta-hydroxysteroid dehydrogenase 13; Short chain dehydrogenase/reductase superfamily | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | 0.514 |
NBPF1 | NBPF3 | ENSP00000474456 | ENSP00000316782 | Neuroblastoma breakpoint family member 1; NBPF member 1 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | 0.708 |
NBPF3 | ABHD12 | ENSP00000316782 | ENSP00000365725 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Monoacylglycerol lipase ABHD12; Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (By similarity). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways; Abhydrolase domain containing | 0.440 |
NBPF3 | ALPL | ENSP00000316782 | ENSP00000363973 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme may play a role in skeletal mineralization; Belongs to the alkaline phosphatase family | 0.800 |
NBPF3 | COL22A1 | ENSP00000316782 | ENSP00000303153 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Collagen alpha-1(XXII) chain; Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts; Belongs to the fibril-associated collagens with interrupted helices (FACIT) family | 0.428 |
NBPF3 | GPLD1 | ENSP00000316782 | ENSP00000230036 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane | 0.430 |
NBPF3 | HSD17B13 | ENSP00000316782 | ENSP00000333300 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | 17-beta-hydroxysteroid dehydrogenase 13; Short chain dehydrogenase/reductase superfamily | 0.514 |
NBPF3 | NBPF1 | ENSP00000316782 | ENSP00000474456 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Neuroblastoma breakpoint family member 1; NBPF member 1 | 0.708 |
NBPF3 | PMFBP1 | ENSP00000316782 | ENSP00000237353 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Polyamine-modulated factor 1-binding protein 1; May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular cytoskeleton | 0.541 |
NBPF3 | TMEM246 | ENSP00000316782 | ENSP00000363984 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Transmembrane protein 246 | 0.445 |
NBPF3 | TRIB1 | ENSP00000316782 | ENSP00000312150 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | Tribbles homolog 1; Adapter protein involved in protein degradation by interacting with RFWD2/COP1 ubiquitin ligase. The RFWD2-binding motif is masked by autoinhibitory interactions with the protein kinase domain. Serves to alter RFWD2 substrate specificity by directing the activity of RFWD2 toward CEBPA. Binds selectively the recognition sequence of CEBPA. Regulates myeloid cell differentiation by altering the expression of CEBPA in a RFWD2- dependent manner (By similarity). Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity). Int [...] | 0.448 |
NBPF3 | TSEN15 | ENSP00000316782 | ENSP00000355299 | Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family | tRNA-splicing endonuclease subunit Sen15; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5’ and 3’ splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2’,3’ cyclic phosphate and 5’-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA bo [...] | 0.547 |