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  • 11.0 [archived version]
STRINGSTRING
OR10A3 OR10A3 EFCAB6 EFCAB6 OVOL1 OVOL1 CAPZA3 CAPZA3 TRIM42 TRIM42 ACTL9 ACTL9 OR2Z1 OR2Z1 C1orf141 C1orf141 SHCBP1L SHCBP1L RBM44 RBM44 CCDC116 CCDC116
"ACTL9" - Actin-like protein 9 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTL9Actin-like protein 9; Actin related proteins (416 aa)    
Predicted Functional Partners:
RBM44
RNA-binding protein 44; Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity); RNA binding motif containing (1052 aa)
      
   
  0.830
OR2Z1
Olfactory receptor 2Z1; Odorant receptor; Olfactory receptors, family 2 (314 aa)
      
   
  0.816
CCDC116
Coiled-coil domain containing 116 (613 aa)
            
  0.783
SHCBP1L
Testicular spindle-associated protein SHCBP1L; Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells (653 aa)
            
  0.681
OVOL1
Putative transcription factor Ovo-like 1; Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system (By similarity); SNAG transcriptional repressors (267 aa)
            
  0.679
C1orf141
Uncharacterized protein C1orf141; Chromosome 1 open reading frame 141 (400 aa)
      
   
  0.664
CAPZA3
F-actin-capping protein subunit alpha-3; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid (By similarity) (299 aa)
      
 
  0.662
TRIM42
Tripartite motif-containing protein 42; Protein phosphatase 1 regulatory subunits; Belongs to the TRIM/RBCC family (723 aa)
      
      0.646
EFCAB6
EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex; EF-hand domain containing (1501 aa)
      
 
  0.636
OR10A3
Olfactory receptor 10A3; Odorant receptor; Olfactory receptors, family 10 (314 aa)
            
  0.631
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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