• Version:
  • 11.0 [archived version]
STRINGSTRING
PEX5L PEX5L PEX5 PEX5 PEX13 PEX13 PEX14 PEX14 PEX2 PEX2 PEX12 PEX12 PEX10 PEX10 PEX1 PEX1 ACAA1 ACAA1 PEX7 PEX7 PEX6 PEX6
"PEX7" - Peroxisomal targeting signal 2 receptor in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PEX7Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import; Belongs to the WD repeat peroxin-7 family (323 aa)    
Predicted Functional Partners:
PEX5
Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import (660 aa)
     
  0.998
PEX13
Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins; Peroxins (403 aa)
     
  0.998
PEX14
Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin; Peroxins (377 aa)
     
  0.998
PEX10
Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes; Peroxins (346 aa)
     
 
  0.996
PEX2
Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family (305 aa)
     
 
  0.995
PEX12
Peroxisome assembly protein 12; Required for protein import into peroxisomes; Peroxins (359 aa)
     
 
  0.994
ACAA1
3-ketoacyl-CoA thiolase, peroxisomal; acetyl-CoA acyltransferase 1 (424 aa)
     
  0.993
PEX5L
PEX5-related protein; Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence; Belongs to the peroxisomal targeting signal receptor family (626 aa)
     
  0.993
PEX6
Peroxisome assembly factor 2; Involved in peroxisome biosynthesis. Required for stability of the PTS1 receptor. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes (980 aa)
     
 
  0.993
PEX1
Peroxisome biogenesis factor 1; Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes (1283 aa)
     
 
  0.987
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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