TMEM25 protein (human) - STRING database

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TMEM25

Transmembrane protein 25; C2-set domain containing (366 aa)

Predicted Functional Partners:

ZDHHC8

0.676

HGD

0.577

TMEM30B

0.548

SLC35G2

0.531

AMZ1

0.523

LPPR5

0.514

EIF5A2

0.507

FAM172A

0.501

ZSCAN18

0.486

MEIG1

0.473

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMZ1	MEIG1	ENSP00000308149	ENSP00000384334	Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family	Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis	0.444
AMZ1	TMEM25	ENSP00000308149	ENSP00000315635	Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family	Transmembrane protein 25; C2-set domain containing	0.523
EIF5A2	TMEM25	ENSP00000295822	ENSP00000315635	Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By s [...]	Transmembrane protein 25; C2-set domain containing	0.507
FAM172A	TMEM25	ENSP00000379294	ENSP00000315635	Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family	Transmembrane protein 25; C2-set domain containing	0.501
HGD	TMEM25	ENSP00000283871	ENSP00000315635	Homogentisate 1,2-dioxygenase	Transmembrane protein 25; C2-set domain containing	0.577
LPPR5	TMEM25	ENSP00000263177	ENSP00000315635	Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family	Transmembrane protein 25; C2-set domain containing	0.514
MEIG1	AMZ1	ENSP00000384334	ENSP00000308149	Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis	Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family	0.444
MEIG1	TMEM25	ENSP00000384334	ENSP00000315635	Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis	Transmembrane protein 25; C2-set domain containing	0.473
SLC35G2	TMEM25	ENSP00000400839	ENSP00000315635	Solute carrier family 35 member G2; May play a role in cell proliferation; Solute carriers	Transmembrane protein 25; C2-set domain containing	0.531
SLC35G2	TMEM30B	ENSP00000400839	ENSP00000450842	Solute carrier family 35 member G2; May play a role in cell proliferation; Solute carriers	Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to th [...]	0.560
TMEM25	AMZ1	ENSP00000315635	ENSP00000308149	Transmembrane protein 25; C2-set domain containing	Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family	0.523
TMEM25	EIF5A2	ENSP00000315635	ENSP00000295822	Transmembrane protein 25; C2-set domain containing	Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By s [...]	0.507
TMEM25	FAM172A	ENSP00000315635	ENSP00000379294	Transmembrane protein 25; C2-set domain containing	Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family	0.501
TMEM25	HGD	ENSP00000315635	ENSP00000283871	Transmembrane protein 25; C2-set domain containing	Homogentisate 1,2-dioxygenase	0.577
TMEM25	LPPR5	ENSP00000315635	ENSP00000263177	Transmembrane protein 25; C2-set domain containing	Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family	0.514
TMEM25	MEIG1	ENSP00000315635	ENSP00000384334	Transmembrane protein 25; C2-set domain containing	Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis	0.473
TMEM25	SLC35G2	ENSP00000315635	ENSP00000400839	Transmembrane protein 25; C2-set domain containing	Solute carrier family 35 member G2; May play a role in cell proliferation; Solute carriers	0.531
TMEM25	TMEM30B	ENSP00000315635	ENSP00000450842	Transmembrane protein 25; C2-set domain containing	Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to th [...]	0.548
TMEM25	ZDHHC8	ENSP00000315635	ENSP00000384716	Transmembrane protein 25; C2-set domain containing	Probable palmitoyltransferase ZDHHC8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily	0.676
TMEM25	ZSCAN18	ENSP00000315635	ENSP00000470123	Transmembrane protein 25; C2-set domain containing	Zinc finger and SCAN domain-containing protein 18; May be involved in transcriptional regulation; SCAN domain containing	0.486

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